COVID-19: coagulopathy, risk of thrombosis, and the rationale for anticoagulation

W Miesbach, M Makris - Clinical and applied thrombosis …, 2020 - journals.sagepub.com
The novel coronavirus infection (COVID-19) is caused by the new coronavirus SARS-CoV-2
and is characterized by an exaggerated inflammatory response that can lead to severe …

Effects of tobacco smoking on cardiovascular disease

T Kondo, Y Nakano, S Adachi, T Murohara - Circulation Journal, 2019 - jstage.jst.go.jp
Tobacco smoking continues to be a major risk factor for cardiovascular disease (CVD) and
the leading avoidable cause of death worldwide. Tobacco smoking has declined in high …

Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism

J Ghouse, V Tragante, G Ahlberg, SA Rand… - Nature …, 2023 - nature.com
We report a genome-wide association study of venous thromboembolism (VTE)
incorporating 81,190 cases and 1,419,671 controls sampled from six cohorts. We identify 93 …

Atrial fibrillation: epidemiology, pathophysiology, and clinical outcomes

L Staerk, JA Sherer, D Ko, EJ Benjamin… - Circulation …, 2017 - Am Heart Assoc
The past 3 decades have been characterized by an exponential growth in knowledge and
advances in the clinical treatment of atrial fibrillation (AF). It is now known that AF genesis …

Global burden of thrombosis: epidemiologic aspects

AM Wendelboe, GE Raskob - Circulation research, 2016 - Am Heart Assoc
Thromboembolic conditions were estimated to account for 1 in 4 deaths worldwide in 2010
and are the leading cause of mortality. Thromboembolic conditions are divided into arterial …

Thrombosis: a major contributor to global disease burden

GE Raskob, P Angchaisuksiri, AN Blanco… - … , and vascular biology, 2014 - Am Heart Assoc
Background—Thrombosis is the common pathology underlying ischemic heart disease,
ischemic stroke, and venous thromboembolism (VTE). The Global Burden of Disease Study …

Prevention of venous thromboembolism in 2020 and beyond

M Nicholson, N Chan, V Bhagirath… - Journal of clinical …, 2020 - mdpi.com
Venous thromboembolism (VTE) is the third most common cause of vascular mortality
worldwide and comprises deep-vein thrombosis (DVT) and pulmonary embolism (PE). In …

Cardiovascular risk factors associated with venous thromboembolism

J Gregson, S Kaptoge, T Bolton, L Pennells… - JAMA …, 2019 - jamanetwork.com
Importance It is uncertain to what extent established cardiovascular risk factors are
associated with venous thromboembolism (VTE). Objective To estimate the associations of …

The hematologic consequences of obesity

JC Purdy, JJ Shatzel - European journal of haematology, 2021 - Wiley Online Library
The prevalence of obesity is increasing and progressively influencing physician‐patient
interactions. While there is a sizable amount of data demonstrating that obesity is a state of …

Genome-wide association study of peripheral artery disease in the Million Veteran Program

D Klarin, J Lynch, K Aragam, M Chaffin, TL Assimes… - Nature medicine, 2019 - nature.com
Peripheral artery disease (PAD) is a leading cause of cardiovascular morbidity and mortality;
however, the extent to which genetic factors increase risk for PAD is largely unknown. Using …