Designing inorganic nanomaterials for vaccines and immunotherapies

KL Hess, IL Medintz, CM Jewell - Nano Today, 2019 - Elsevier
Vaccines and immunotherapies have changed the face of health care. Biomaterials offer the
ability to improve upon these medical technologies through increased control of the types …

IL-27-induced modulation of autoimmunity and its therapeutic potential

RR Meka, SH Venkatesha, S Dudics, B Acharya… - Autoimmunity …, 2015 - Elsevier
Abstract Interleukin-27 (IL-27) is a new member of the IL-12 family. It is produced by
activated antigen-presenting cells and plays an important role in the regulation of CD4+ T …

Activating cannabinoid receptor 2 alleviates pathogenesis of experimental autoimmune encephalomyelitis via activation of autophagy and inhibiting NLRP 3 …

BZ Shao, W Wei, P Ke, ZQ Xu… - CNS neuroscience & …, 2014 - Wiley Online Library
Aims Activation of cannabinoid receptor 2 (CB 2R) has been reported to ameliorate the
pathogenesis of experimental autoimmune encephalomyelitis (EAE). In this study, we …

Role of inflammasomes in neuroimmune and neurodegenerative diseases: a systematic review

Y Lang, F Chu, D Shen, W Zhang… - Mediators of …, 2018 - Wiley Online Library
Inflammasomes are multiprotein complexes that can sense pathogen‐associated molecular
patterns and damage‐associated molecular signals. They are involved in the initiation and …

Immunotherapeutic nanoparticles: From autoimmune disease control to the development of vaccines

R Mitarotonda, E Giorgi, T Eufrasio-da-Silva… - Biomaterials …, 2022 - Elsevier
The development of nanoparticles (NPs) with potential therapeutic uses represents an area
of vast interest in the scientific community during the last years. Recently, the pandemic …

Immunomodulation, toxicity, and therapeutic potential of nanoparticles

A Pandey, AK Mishra - BioTech, 2022 - mdpi.com
Altered immune responses associated with human disease conditions, such as inflammatory
and infectious diseases, cancers, and autoimmune diseases, are among the primary causes …

The regulatory mechanism and potential application of IL-23 in autoimmune diseases

DK Xiong, X Shi, MM Han, XM Zhang, NN Wu… - Frontiers in …, 2022 - frontiersin.org
IL-23 is a heterodimeric pro-inflammatory cytokine secreted by dendritic cells and
macrophages that belongs to the IL-12 family. It has pro-inflammatory effects and is a key …

[HTML][HTML] Nanostructured Drug Delivery Systems in Immunotherapy: An Updated Overview of Nanotechnology-Based Therapeutic Innovations

GA Croitoru, AG Niculescu, D Epistatu, DE Mihaiescu… - Applied Sciences, 2024 - mdpi.com
Using nanostructured drug delivery systems has attracted increasing interest in
immunotherapeutic approaches. The intrinsic immunomodulatory properties and versatility …

The pathological mechanism and potential application of IL-38 in autoimmune diseases

M Han, X Yuan, X Shi, XY Zhu, Y Su… - Frontiers in …, 2021 - frontiersin.org
Interleukin-38 (IL-38), a new cytokine of interleukin-1 family (IL-1F), is expressed in the
human heart, kidney, skin, etc. Recently, new evidence indicated that IL-38 is involved in the …

Activating α7 nicotinic acetylcholine receptor inhibits NLRP 3 inflammasome through regulation of β‐arrestin‐1

P Ke, BZ Shao, ZQ Xu, XW Chen… - CNS Neuroscience & …, 2017 - Wiley Online Library
Aims To evaluate whether activating α7 nicotinic acetylcholine receptor (α7n AC hR) could
inhibit the NOD‐like receptor family, pyrin domain containing 3 (NLRP 3) inflammasome …