Alterations in olfactory functions are proposed to be early biomarkers for neurodegeneration.
Many neurodegenerative diseases are age-related, including two of the most common …

C. elegans has a highly developed chemosensory system that enables it to detect a wide
variety of volatile (olfactory) and water-soluble (gustatory) cues associated with food …

Comprehensively resolving neuronal identities in whole-brain images is a major challenge.
We achieve this in C. elegans by engineering a multicolor transgene called NeuroPAL (a …

Caenorhabditis elegans explores its environment by interrupting its forward movement with
occasional turns and reversals. Turns and reversals occur at stable frequencies but irregular …

Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

Innate social behaviours emerge from neuronal circuits that interpret sensory information on
the basis of an individual's own genotype, sex and experience. The regulated aggregation …

The ability to react to environmental change is crucial for the survival of an organism and an
essential prerequisite is the capacity to detect and respond to aversive stimuli. The …

The nematode Caenorhabditis elegans is present in soils and composts, where it can
encounter a variety of microorganisms. Some bacteria in these rich environments are …

A current challenge in neuroscience is to bridge the gaps between genes, proteins, neurons,
neural circuits, and behavior in a single animal model. The nematode Caenorhabditis …

C. elegans OSM-9 is a TRPV channel protein involved in sensory transduction and
adaptation. Here, we show that distinct sensory functions arise from different combinations of …