Selenium: From fluorescent probes to biomedical application
Selenium (Se) is of fundamental importance to human health as an essential trace element,
mainly through regulation of selenoproteins (SePs). Therefore, monitoring Se transformation …
mainly through regulation of selenoproteins (SePs). Therefore, monitoring Se transformation …
High-throughput fluorescent screening of thioredoxin reductase inhibitors to inhibit Mycobacterium tuberculosis
F Yan, X Zhao, R Li, X Han, Q Yan, L Feng, X Xin… - Chinese Chemical …, 2024 - Elsevier
Tuberculosis (TB) is a chronic infectious disease, which is caused by the pathogen
Mycobacterium tuberculosis (Mtb) and reemerged as a global health risk with a significant …
Mycobacterium tuberculosis (Mtb) and reemerged as a global health risk with a significant …
Selective cellular probes for mammalian thioredoxin reductase TrxR1: rational design of RX1, a modular 1, 2-thiaselenane redox probe
Quantifying the activity of key cellular redox players is crucial for understanding
physiological homeostasis and for targeting their perturbed states in pathologies, including …
physiological homeostasis and for targeting their perturbed states in pathologies, including …
Cold plasma pretreatment reinforces the lignocellulose-derived aldehyde inhibitors tolerance and bioethanol fermentability for Zymomonas mobilis
X Yi, D Yang, X Xu, Y Wang, Y Guo, M Zhang… - … for Biofuels and …, 2023 - Springer
Background Lignocellulose-derived aldehyde inhibitors seriously blocked the biorefinery of
biofuels and biochemicals. To date, the economic production of lignocellulose-based …
biofuels and biochemicals. To date, the economic production of lignocellulose-based …
A fluorescent probe to detect quick disulfide reductase activity in bacteria
Y Zhao, X Zuo, S Liu, W Qian, X Tang, J Lu - Antioxidants, 2022 - mdpi.com
The Trx and Grx systems, two disulfide reductase systems, play critical roles in various cell
activities. There are great differences between the thiol redox systems in prokaryotes and …
activities. There are great differences between the thiol redox systems in prokaryotes and …
Glutaredoxin 2 in the mud crab Scylla paramamosain: Identification and functional characterization under hypoxia and pathogen challenge
YK Jie, HL Ma, JJ Jiang, CH Cheng, YQ Deng… - Developmental & …, 2023 - Elsevier
Glutaredoxin (Grx) is a glutathione-dependent oxidoreductase that plays a key role in
antioxidant defense. In this study, a novel Grx2 gene (SpGrx2) was identified from the mud …
antioxidant defense. In this study, a novel Grx2 gene (SpGrx2) was identified from the mud …
Identification of thioredoxin-1 as a biomarker of lung cancer and evaluation of its prognostic value based on bioinformatics analysis
X Liu, X Dong, Y Hu, Y Fang - Frontiers in Oncology, 2023 - frontiersin.org
Background Thioredoxin-1 (TXN), a redox balance factor, plays an essential role in oxidative
stress and has been shown to act as a potential contributor to various cancers. This study …
stress and has been shown to act as a potential contributor to various cancers. This study …
Benzothiophene-based Fragments Act as Reversible and Irreversible Covalent Probes for Dynamic Coactivator Med25
P Williams - 2023 - deepblue.lib.umich.edu
Transcriptional coactivators mediate transcriptional activity within cells by forming transient
protein-protein interactions (PPIs) to facilitate the assembly of the RNA polymerase …
protein-protein interactions (PPIs) to facilitate the assembly of the RNA polymerase …
Fluorescent Probes for Mammalian Thioredoxin Reductase: Mechanistic Analysis, Construction Strategies, and Future Perspectives
Z Song, C Fan, J Zhao, L Wang, D Duan, T Shen, X Li - Biosensors, 2023 - mdpi.com
The modulation of numerous signaling pathways is orchestrated by redox regulation of
cellular environments. Maintaining dynamic redox homeostasis is of utmost importance for …
cellular environments. Maintaining dynamic redox homeostasis is of utmost importance for …