Micronucleus assay: the state of art, and future directions
S Sommer, I Buraczewska, M Kruszewski - International journal of …, 2020 - mdpi.com
During almost 40 years of use, the micronucleus assay (MN) has become one of the most
popular methods to assess genotoxicity of different chemical and physical factors, including …
popular methods to assess genotoxicity of different chemical and physical factors, including …
Putative origins of cell-free DNA in humans: a review of active and passive nucleic acid release mechanisms
S Grabuschnig, AJ Bronkhorst, S Holdenrieder… - International journal of …, 2020 - mdpi.com
Through various pathways of cell death, degradation, and regulated extrusion, partial or
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …
Catastrophic nuclear envelope collapse in cancer cell micronuclei
EM Hatch, AH Fischer, TJ Deerinck, MW Hetzer - Cell, 2013 - cell.com
During mitotic exit, missegregated chromosomes can recruit their own nuclear envelope
(NE) to form micronuclei (MN). MN have reduced functioning compared to primary nuclei in …
(NE) to form micronuclei (MN). MN have reduced functioning compared to primary nuclei in …
Micronuclei as biomarkers of DNA damage, aneuploidy, inducers of chromosomal hypermutation and as sources of pro-inflammatory DNA in humans
M Fenech, S Knasmueller, C Bolognesi… - … Research/Reviews in …, 2020 - Elsevier
Micronuclei (MNi) are among the most widely studied biomarkers of DNA damage and
chromosomal instability in humans. They originate from chromosome fragments or intact …
chromosomal instability in humans. They originate from chromosome fragments or intact …
Resveratrol and neuroprotection: impact and its therapeutic potential in Alzheimer's disease
Alzheimer's disease (AD) is a progressive cortex and hippocampal neurodegenerative
disease which ultimately causes cognitively impaired decline in patients. The AD pathogen …
disease which ultimately causes cognitively impaired decline in patients. The AD pathogen …
Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside
Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …
Buccal micronucleus cytome assay
P Thomas, N Holland, C Bolognesi, M Kirsch-Volders… - Nature protocols, 2009 - nature.com
Abstract The Buccal Micronucleus Cytome (BMCyt) assay is a minimally invasive method for
studying DNA damage, chromosomal instability, cell death and the regenerative potential of …
studying DNA damage, chromosomal instability, cell death and the regenerative potential of …
The HUman MicroNucleus project on eXfoLiated buccal cells (HUMNXL): The role of life-style, host factors, occupational exposures, health status, and assay protocol
The human buccal micronucleus cytome assay (BMCyt) is one of the most widely used
techniques to measure genetic damage in human population studies. Reducing protocol …
techniques to measure genetic damage in human population studies. Reducing protocol …
[HTML][HTML] Protective effects of micronutrient supplements, phytochemicals and phytochemical-rich beverages and foods against DNA damage in humans: a systematic …
MF Fenech, CF Bull, BJW Van Klinken - Advances in Nutrition, 2023 - Elsevier
Accumulation of deoxyribonucleic acid (DNA) damage diminishes cellular health, increases
risk of developmental and degenerative diseases, and accelerates aging. Optimizing …
risk of developmental and degenerative diseases, and accelerates aging. Optimizing …
The HUMNxl scoring criteria for different cell types and nuclear anomalies in the buccal micronucleus cytome assay–An update and expanded photogallery
C Bolognesi, S Knasmueller, A Nersesyan… - … Research/Reviews in …, 2013 - Elsevier
The buccal micronucleus cytome assay is a minimally invasive cytological and interphase
cytogenetic technique for measuring DNA damage and cell death biomarkers in the oral …
cytogenetic technique for measuring DNA damage and cell death biomarkers in the oral …