Post-stroke cognitive impairment and dementia

NS Rost, A Brodtmann, MP Pase, SJ van Veluw… - Circulation …, 2022 - Am Heart Assoc
Poststroke cognitive impairment and dementia (PSCID) is a major source of morbidity and
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke …

The role of the medial prefrontal cortex in cognition, ageing and dementia

DD Jobson, Y Hase, AN Clarkson… - Brain …, 2021 - academic.oup.com
Humans require a plethora of higher cognitive skills to perform executive functions, such as
reasoning, planning, language and social interactions, which are regulated predominantly …

Rehmannioside A improves cognitive impairment and alleviates ferroptosis via activating PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway after ischemia

C Fu, Y Wu, S Liu, C Luo, Y Lu, M Liu, L Wang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Rehmannioside A is derived from Rehmannia glutinosa
Libosch, which is widely used as an important ingredient in diverse traditional Chinese …

Incidence and prevalence of dementia associated with transient ischaemic attack and stroke: analysis of the population-based Oxford Vascular Study

ST Pendlebury, PM Rothwell - The Lancet Neurology, 2019 - thelancet.com
Background Risk of dementia after stroke is a major concern for patients and carers.
Reliable data for risk of dementia, particularly after transient ischaemic attack or minor …

Vascular dementia

JT O'Brien, A Thomas - The Lancet, 2015 - thelancet.com
Vascular dementia is one of the most common causes of dementia after Alzheimer's
disease, causing around 15% of cases. However, unlike Alzheimer's disease, there are no …

Vascular cognitive impairment

M Dichgans, D Leys - Circulation research, 2017 - Am Heart Assoc
Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …

[HTML][HTML] Stroke injury, cognitive impairment and vascular dementia

RN Kalaria, R Akinyemi, M Ihara - … Acta (BBA)-Molecular Basis of Disease, 2016 - Elsevier
The global burden of ischaemic strokes is almost 4-fold greater than haemorrhagic strokes.
Current evidence suggests that 25–30% of ischaemic stroke survivors develop immediate or …

The pathology and pathophysiology of vascular dementia

RN Kalaria - Neuropharmacology, 2018 - Elsevier
Vascular dementia (VaD) is widely recognised as the second most common type of
dementia. Consensus and accurate diagnosis of clinically suspected VaD relies on wide …

The pathobiology of vascular dementia

C Iadecola - Neuron, 2013 - cell.com
Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …

Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer's disease

RN Kalaria - Acta neuropathologica, 2016 - Springer
Vascular dementia (VaD) is recognised as a neurocognitive disorder, which is explained by
numerous vascular causes in the general absence of other pathologies. The heterogeneity …