Sustained hepatic inflammation is an important factor in progression of chronic liver
diseases, including hepatitis C or non-alcoholic steatohepatitis. Liver inflammation is …

During hepatitis B virus (HBV) infection, the presence of HBV-specific antibody producing B
cells and functional HBV-specific T cells (with helper or cytotoxic effects) ultimately …

B cells are increasingly recognized as playing an important role in the ongoing control of
hepatitis B virus (HBV). The development of antibodies against the viral surface antigen …

Chronic HBV (CHB) infection suppresses virus-specific T cells, but its impact on humoral
immunity has been poorly analyzed. Here, we developed a dual-staining method that …

A regulatory subset of B cells has been found to modulate immune responses in
autoimmunity, infection, and cancer, but it has not been investigated in the setting of human …

HBsAg seroclearance occurs rarely in the natural history of chronic hepatitis B (CHB)
infection and is associated with improved clinical outcomes. Many factors are associated …

This study aimed to examine the frequency of different subsets of circulating B and T
follicular helper (Tfh) cells in patients with new-onset rheumatoid arthritis (RA) and following …

Objective The investigation regarding the clinical significance of quantitative hepatitis B core
antibody (anti-HBc) during chronic hepatitis B (CHB) treatment is limited. The aim of this …

While new therapies for chronic hepatitis C virus infection have delivered remarkable cure
rates, curative therapies for chronic hepatitis B virus (HBV) infection remain a distant goal …

The liver's unique characteristics have a profound impact on the priming and maintenance of
adaptive immunity. This review delves into the cellular circuits that regulate adaptive …