The international consortium detected a full-length transcript of 3· 7 kb encoding a protein
consisting of 781 aminoacids. This protein product was termed “pyrin”, indicating its relation …

The TRIM/RBCC proteins are defined by the presence of the tripartite motif composed of a
RING domain, one or two B‐box motifs and a coiled‐coil region. These proteins are involved …

A strong candidate for the 17q-linked BRCA1 gene, which influences susceptibility to breast
and ovarian cancer, has been identified by positional cloning methods. Probable …

Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by
attacks of fever and serositis. In this paper, we define a minimal co-segregating region of 60 …

Familial Mediterranean fever (FMF) is a recessively inherited disorder characterized by
dramatic episodes of fever and serosal inflammation. This report describes the cloning of the …

A unique mRNA produced in leukemic cells from at (15; 17) acute promyelocytic leukemia
(APL) patient encodes a fusion protein between the retinoic acid receptor a (RARa) and a …

We have identified a novel protein, BAP1, which binds to the RING finger domain of the
Breast/Ovarian Cancer Susceptibility Gene product, BRCA1. BAP1 is a nuclear-localized …

MO-MLV infection of Ep-myc transgenic mice results in a dramatic acceleration of pre-B ceil
iymphomagenesis. We have used provirus tagging to identify genes that cooperate with the …

We have previously shown that the t (15; 17) translocation specifically associated with acute
promyelocytic leukemra (APL) fuses the retinoic acid receptor a (RARa) locus to an as yet …

Plant seedling development is capable of following 1 of 2 distinct morphogenic pathways:
skotomorphogenesis in darknessand photomorphogenesis in light. Dark-grown Arabidopsis …