The term functionalized isocyanides refers to all those isocyanides in which a neighbouring
functional group can finely tune the reactivity of the isocyano group or can be exploited in …

Polyheterocycles are one of the most desired synthetic targets due to their numerous and
valuable applications in various fields. Multicomponent reactions (MCRs) are highly …

The isocyanide functionality due to its dichotomy between carbenoid and triple bond
characters, with a nucleophilic and electrophilic terminal carbon, exhibits unusual reactivity …

The α-ketoamide motif is widely found in many natural products and drug candidates with
relevant biological activities. Furthermore, α-ketoamides are attractive candidates to …

Seven-and eight-membered rings widely exist in natural products and drugs. Considering
the transition state nonbonding interactions and torsional strains, the flexible conformations …

A one-pot process has been developed for preparing alkaloid-like tricyclic skeletons by
employing an Ugi reaction, an acid mediated ipso-cyclization and an aza-Michael addition …

This is the first review describing all the quinoxaline–benzimidazole rearrangements as a
whole and the new quinoxalinone–benzimidazol (on) e rearrangements in particular when …

In this report, we try to show the importance of incorporation of name reactions in the
sequential cascade reaction in which significantly decreasing the number of steps towards …

The total syntheses of selected natural products using different versions of the Ugi
multicomponent reaction is reviewed on a case-by-case basis. The revision covers the …

This year represents the 100th anniversary of the discovery of the Passerini three-
component reaction. The related Ugi four-compound reaction was discovered 37 years after …