Recent applications of near-infrared spectroscopy in cancer diagnosis and therapy

VR Kondepati, HM Heise, J Backhaus - Analytical and bioanalytical …, 2008 - Springer
In recent years, near-infrared spectroscopy (NIRS) has gained importance for non-invasive
or minimally invasive diagnostic applications in cancer. This technology is based on …

19F: a versatile reporter for non-invasive physiology and pharmacology using magnetic resonance

J Yu, VD Kodibagkar, W Cui… - Current medicinal …, 2005 - ingentaconnect.com
The fluorine atom provides an exciting tool for diverse spectroscopic and imaging
applications using Magnetic Resonance. The organic chemistry of fluorine is widely …

ARCON: experience in 215 patients with advanced head-and-neck cancer

JHAM Kaanders, LAM Pop, HAM Marres… - International Journal of …, 2002 - Elsevier
Purpose:“ARCON” combines accelerated radiotherapy to counteract tumor repopulation with
carbogen breathing and nicotinamide to reduce chronic and acute hypoxia. The aim of this …

Measuring changes in tumor oxygenation

D Zhao, L Jiang, RP Mason - Methods in enzymology, 2004 - Elsevier
Publisher Summary This chapter discusses the measurement of changes in tumor
oxygenation. The oxygen pressure determinations could be of great clinical value and they …

Tumor vascular architecture and function evaluated by non‐invasive susceptibility MRI methods and immunohistochemistry

SP Robinson, PFJW Rijken, FA Howe… - Journal of Magnetic …, 2003 - Wiley Online Library
Purpose To investigate the physiological origins responsible for the varying blood
oxygenation level dependent (BOLD) magnetic resonance imaging (MRI) responses to …

Effects of breathing a hyperoxic hypercapnic gas mixture on blood oxygenation and vascularity of head-and-neck tumors as measured by magnetic resonance …

M Rijpkema, JHAM Kaanders, FBM Joosten… - International Journal of …, 2002 - Elsevier
Purpose: For head-and-neck tumors, breathing a hyperoxic hypercapnic gas mixture and
administration of nicotinamide has been shown to result in a significantly improved tumor …

Tumor oximetry: demonstration of an enhanced dynamic mapping procedure using fluorine-19 echo planar magnetic resonance imaging in the Dunning prostate …

S Hunjan, D Zhao, A Constantinescu, EW Hahn… - International Journal of …, 2001 - Elsevier
Purpose: We have developed an enhanced approach to measuring regional oxygen tension
(pO2) dynamics in tumors. The technique is demonstrated in a group of 8 Dunning prostate …

Changes in tumor oxygenation/perfusion induced by the no donor, isosorbide dinitrate, in comparison with carbogen: monitoring by EPR and MRI

BF Jordan, PD Misson, R Demeure, C Baudelet… - International Journal of …, 2000 - Elsevier
Purpose: In an effort to improve radiotherapy treatments, methods aimed at increasing the
quantity of oxygen delivered to tumors were investigated. The aim of this study was to …

Changes in oxygenation of intracranial tumors with carbogen: a BOLD MRI and EPR oximetry study

JF Dunn, JA O'Hara, Y Zaim‐Wadghiri… - Journal of Magnetic …, 2002 - Wiley Online Library
Purpose To examine, using blood oxygen level dependent (BOLD) MRI and EPR oximetry,
the changes in oxygenation of intracranial tumors induced by carbogen breathing. Materials …

Insulin increases the sensitivity of tumors to irradiation: involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor …

BF Jordan, V Grégoire, RJ Demeure, P Sonveaux… - Cancer research, 2002 - AACR
The effects of insulin on tumor oxygenation, perfusion, oxygen consumption, and radiation
sensitivity were studied on two different mouse tumor models (TLT, a liver tumor, and FSAII …