The protective effect of crocin on cisplatin-induced testicular impairment in rats

B Mesbahzadeh, M Hassanzadeh-Taheri, M Aliparast… - Bmc Urology, 2021 - Springer
Background Side effects of cisplatin (CIS) such as testicular toxicity restrict its clinical use.
Instead, evidence indicates that crocin (CR) has synergistic anti-cancer potential with CIS …

[HTML][HTML] Effect of thymoquinone on reproductive parameter in morphine-treated male mice

MR Salahshoor, M Haghjoo… - Advanced biomedical …, 2018 - journals.lww.com
Background: Thymoquinone as the main active component of Nigella sativa might have a
various pharmacological effects such as antiapoptotic and antioxidant. Morphine is …

Effect of Falcaria vulgaris extracts on sperm parameters in diabetic rats

C Jalili, M Kamani, S Roshankhah, H Sadeghi… - Andrologia, 2018 - Wiley Online Library
Diabetes causes a systemic inflammatory response with increased oxidative stress and can
adversely effect spermatogenesis. Sickle‐weed plant, scientifically called Falcaria vlugaris …

Protective effects of crocin on acrylamide‐induced testis damage

M Gül, E Kayhan Kuştepe, ME Erdemli, E Altınöz… - Andrologia, 2021 - Wiley Online Library
Exposure to acrylamide (Ac) through food is almost inevitable and this kind of toxicity may
cause lifelong harm. In present study, we researched effects of Crocin (Cr) on testis …

[HTML][HTML] Effect of crocin on biochemical parameters, oxidative/antioxidative profiles, sperm characteristics and testicular histopathology in streptozotocin-induced …

SM Sefidgar, M Ahmadi-Hamedani… - Avicenna Journal of …, 2019 - ncbi.nlm.nih.gov
Objective: Chronic hyperglycemia and overproduction of reactive oxygen species (ROS) are
strong predictors of the development of reproductive complications of diabetes. The present …

The protective effect of crocin against testicular toxicity induced by ionizing radiation via AKT/FOXO pathway

MM El‐Sheikh, MM Aziz… - Environmental …, 2023 - Wiley Online Library
Crocin, a pharmacologically active component of Crocus sativus L.(saffron), has been
informed to be beneficial in the treatment of stress‐related oxidative impairment. In the …

[HTML][HTML] Effects of crocin on sperm parameters and seminiferous tubules in diabetic rats

S Roshankhah, C Jalili… - Advanced biomedical …, 2019 - journals.lww.com
Background: Diabetes can increase the generation of free radicals and can be harmfully
effective in spermatogenesis. Crocin is a carotenoid and is accountable for the red color of …

[HTML][HTML] Protective effect of crocin on electromagnetic field-induced testicular damage and heat shock protein A2 expression in male BALB/c mice

S Vafaei, F Motejaded… - Iranian Journal of Basic …, 2020 - ncbi.nlm.nih.gov
Objective (s): Exposure to electromagnetic fields (EMF) emitted from mobile phones may
cause a deleterious effect on human health and may affect the male reproductive system …

Nigella sativa-Floral Honey and Multi-Floral Honey versus Nigella sativa Oil against Testicular Degeneration Rat Model: The Possible Protective Mechanisms

MS Almujaydil, RM Algheshairy, RM Alhomaid… - Nutrients, 2023 - mdpi.com
The male reproductive function, particularly the testes, and the related hormones are
sensitive to various xenobiotics. This work aimed for the first time to assess Nigella sativa …

[HTML][HTML] The effect of crocin on testicular tissue and sperm parameters of mice offspring from mothers exposed to atrazine during pregnancy and lactation periods: An …

M Fani, A Mohammadipour… - International journal …, 2018 - ncbi.nlm.nih.gov
Background: Atrazine as a herbicide may affect the human's health. Crocin may protect
atrazine-induced damages. Objective: The aim of this study was to evaluate the effects of …