Datura Metel L. Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis and Inhibits Inflammatory Cytokines Production through TLR7/8–MyD88–NF-κB–NLRP3 …
BY Yang, YG Cheng, Y Liu, Y Liu, JY Tan, W Guan… - Molecules, 2019 - mdpi.com
Background: Psoriasis is a chronic, immune-mediated inflammatory skin disease, and the
inflammatory response plays an important role in its development and progression. Datura …
inflammatory response plays an important role in its development and progression. Datura …
Single-cell transcriptomic landscape of immunometabolism reveals intervention candidates of ascorbate and aldarate metabolism, fatty-acid degradation and PUFA …
L Peng, L Chen, J Wan, W Liu, S Lou… - Frontiers in …, 2023 - frontiersin.org
Introduction The modulation of immunometabolic pathways is emerging as a promising
therapeutic target for immune-mediated diseases. However, the immunometabolic features …
therapeutic target for immune-mediated diseases. However, the immunometabolic features …
Tetrahexyldecyl ascorbate (THDC) degrades rapidly under oxidative stress but can be stabilized by acetyl zingerone to enhance collagen production and antioxidant …
WR Swindell, M Randhawa, G Quijas… - International journal of …, 2021 - mdpi.com
Tetrahexyldecyl Ascorbate (THDC) is an L-ascorbic acid precursor with improved stability
and ability to penetrate the epidermis. The stability and transdermal penetration of THDC …
and ability to penetrate the epidermis. The stability and transdermal penetration of THDC …
Protective Mechanism of Fagopyrum esculentum Moench. Bee Pollen EtOH Extract Against Type II Diabetes in a High-Fat Diet/Streptozocin-Induced C57BL/6J Mice
J Zhang, W Cao, H Zhao, S Guo, Q Wang… - Frontiers in …, 2022 - frontiersin.org
Bee pollen is known as a natural nutrient storehouse and plays a key role in many biological
processes. Based on the preliminary separation, identification, and characterization of the …
processes. Based on the preliminary separation, identification, and characterization of the …
Loss of the epigenetic mark 5-hmC in psoriasis: implications for epidermal stem cell dysregulation
Epigenetic regulation has a profound influence on stem cell fate during normal development
in maintenance of physiologic tissue homeostasis. Here we report diminished ten-eleven …
in maintenance of physiologic tissue homeostasis. Here we report diminished ten-eleven …
Interaction of carbon dots with endothelial cells: implications for biomedical applications
The in vivo use of carbon dots (CDs) in biomedical applications might result in its interaction
with the endothelial cells (ECs) lining the blood vessels. It is important to assess its response …
with the endothelial cells (ECs) lining the blood vessels. It is important to assess its response …
[HTML][HTML] Protective effect and regulatory mechanism of salidroside on skin inflammation induced by imiquimod in psoriasis mice
Z Su, Y Kang - Journal of Pharmacological Sciences, 2024 - Elsevier
Salidroside (SAL) is a glucoside of tyrosol commonly existing in the roots of Rhodiola rosea.
This study unveils the protective effect of SAL on skin inflammation in imiquimod (IMQ) …
This study unveils the protective effect of SAL on skin inflammation in imiquimod (IMQ) …
The Model of PPARγ‐Downregulated Signaling in Psoriasis
V Sobolev, A Nesterova, A Soboleva… - PPAR …, 2020 - Wiley Online Library
Interactions of genes in intersecting signaling pathways, as well as environmental
influences, are required for the development of psoriasis. Peroxisome proliferator‐activated …
influences, are required for the development of psoriasis. Peroxisome proliferator‐activated …
4‐Sulfonyloxy/alkoxy benzoxazolone derivatives with high anti‐inflammatory activities: Synthesis, biological evaluation, and mechanims of action via p38/ERK‐NF‐κB …
L Tang, J Luo, X Wang, B Zhao, R Ge… - Chemical Biology & …, 2021 - Wiley Online Library
In an effort to discover new agents with high anti‐inflammatory activity, 22 new 4‐
sulfonyloxy/alkoxy benzoxazolone derivatives were synthesized, characterized, and …
sulfonyloxy/alkoxy benzoxazolone derivatives were synthesized, characterized, and …
Anti‐allergic effect of ascorbic acid derivative DDH‐1 in a mouse model of atopic dermatitis
K Kitahata, K Matsuo, M Sato, Y Susami… - Experimental …, 2022 - Wiley Online Library
Atopic dermatitis (AD) is the most common inflammatory skin disease, which is characterized
by excessive Th2 immune responses. In AD patients, the expression of the chemokines …
by excessive Th2 immune responses. In AD patients, the expression of the chemokines …