Genetic drift, selection and the evolution of the mutation rate

M Lynch, MS Ackerman, JF Gout, H Long… - Nature Reviews …, 2016 - nature.com
As one of the few cellular traits that can be quantified across the tree of life, DNA-replication
fidelity provides an excellent platform for understanding fundamental evolutionary …

Evolvability: A quantitative-genetics perspective

TF Hansen, C Pélabon - Annual Review of Ecology, Evolution …, 2021 - annualreviews.org
The concept of evolvability emerged in the early 1990s and soon became fashionable as a
label for different streams of research in evolutionary biology. In evolutionary quantitative …

Evolution of coastal forests based on a full set of mangrove genomes

Z He, X Feng, Q Chen, L Li, S Li, K Han, Z Guo… - Nature ecology & …, 2022 - nature.com
Genomic studies are now poised to explore whole communities of species. The~ 70 species
of woody plants that anchor the coastal ecosystems of the tropics, collectively referred to as …

[图书][B] The ecology of adaptive radiation

D Schluter - 2000 - books.google.com
Adaptive radiation is the evolution of diversity within a rapidly multiplying lineage. It can
cause a single ancestral species to differentiate into an impressively vast array of species …

A quantitative survey of local adaptation and fitness trade-offs

J Hereford - The American Naturalist, 2009 - journals.uchicago.edu
The long history of reciprocal transplant studies testing the hypothesis of local adaptation
has shown that populations are often adapted to their local environments. Yet many studies …

Rate, molecular spectrum, and consequences of human mutation

M Lynch - Proceedings of the National Academy of …, 2010 - National Acad Sciences
Although mutation provides the fuel for phenotypic evolution, it also imposes a substantial
burden on fitness through the production of predominantly deleterious alleles, a matter of …

The distribution of fitness effects of new mutations

A Eyre-Walker, PD Keightley - Nature Reviews Genetics, 2007 - nature.com
The distribution of fitness effects (DFE) of new mutations is a fundamental entity in genetics
that has implications ranging from the genetic basis of complex disease to the stability of the …

Mutation and human exceptionalism: our future genetic load

M Lynch - Genetics, 2016 - academic.oup.com
Although the human germline mutation rate is higher than that in any other well-studied
species, the rate is not exceptional once the effective genome size and effective population …

[图书][B] Evolution: Probleme—Themen—Fragen

M Ridley - 2013 - books.google.com
Beim Studium der jüngeren Kontroversen über den Darwinismus fiel mir wiederholt auf, das
sie falsche Darstellungen enthielten, so als würde es sich um irgendetwas Umfassenderes …

Drift-barrier hypothesis and mutation-rate evolution

W Sung, MS Ackerman, SF Miller… - Proceedings of the …, 2012 - National Acad Sciences
Mutation dictates the tempo and mode of evolution, and like all traits, the mutation rate is
subject to evolutionary modification. Here, we report refined estimates of the mutation rate …