[HTML][HTML] Parkinson's disease and the environment
Parkinson's disease (PD) is a heterogeneous neurodegenerative disorder that affects an
estimated 10 million sufferers worldwide. The two forms of PD include familial and sporadic …
estimated 10 million sufferers worldwide. The two forms of PD include familial and sporadic …
Protective role of IGF-1 and GLP-1 signaling activation in neurological dysfunctions
Abstract Insulin-like growth factor-1 (IGF-1), a pleiotropic polypeptide, plays an essential role
in CNS development and maturation. Glucagon-like peptide-1 (GLP-1) is an endogenous …
in CNS development and maturation. Glucagon-like peptide-1 (GLP-1) is an endogenous …
[HTML][HTML] Cardiac changes in Parkinson's disease: lessons from clinical and experimental evidence
L Cuenca-Bermejo, P Almela… - International Journal of …, 2021 - mdpi.com
Dysautonomia is a common non-motor symptom in Parkinson's disease (PD). Most
dysautonomic symptoms appear due to alterations in the peripheral nerves of the autonomic …
dysautonomic symptoms appear due to alterations in the peripheral nerves of the autonomic …
Ageing, the autonomic nervous system and arrhythmia: from brain to heart
An ageing myocardium possesses significant electrophysiological alterations that
predisposes the elderly patient to arrhythmic risk. Whilst these alterations are intrinsic to the …
predisposes the elderly patient to arrhythmic risk. Whilst these alterations are intrinsic to the …
Epiisopiloturine, an Alkaloid from Pilocarpus microphyllus, Attenuates LPS‐Induced Neuroinflammation by Interfering in the TLR4/NF‐κB‐MAPK Signaling Pathway …
JAC de Sousa, FVCS Azul, AB de Araújo… - Oxidative Medicine …, 2023 - Wiley Online Library
Neuroinflammation is present in the pathophysiological mechanisms of several diseases
that affect the central nervous system (CNS). Microglia have a prominent role in initiating …
that affect the central nervous system (CNS). Microglia have a prominent role in initiating …
[HTML][HTML] Sudden unexpected death in Parkinson's disease: Insights from clinical practice
FA Scorza, M Guimaraes-Marques, M Nejm… - Clinics, 2022 - SciELO Brasil
Classified as the second most common neurodegenerative disorder associated with aging
after Alzheimer's disease, Parkinson's disease (PD) is the most common movement …
after Alzheimer's disease, Parkinson's disease (PD) is the most common movement …
[HTML][HTML] Circadian clock disruption promotes the degeneration of dopaminergic neurons in male Drosophila
M Majcin Dorcikova, LC Duret, E Pottié… - Nature …, 2023 - nature.com
Sleep and circadian rhythm disruptions are frequent comorbidities of Parkinson's disease
(PD), a disorder characterized by the progressive loss of dopaminergic (DA) neurons in the …
(PD), a disorder characterized by the progressive loss of dopaminergic (DA) neurons in the …
Uncovering the Molecular Link Between Lead Toxicity and Parkinson's Disease
Significance: Parkinson's disease (PD) is a progressive neurodegenerative disorder that
affects millions around the world. The etiology of PD remains unknown, but environmental …
affects millions around the world. The etiology of PD remains unknown, but environmental …
[HTML][HTML] Biomonitoring of toxic metals in feathers of birds from North-Eastern Pakistan
The current study was designed to determine the concentrations of toxic metals (Ni, Pb and
Cr) in feathers of birds collected from four regions of NE Pakistan. Feather samples of birds …
Cr) in feathers of birds collected from four regions of NE Pakistan. Feather samples of birds …
An investigation of the anti-Parkinsonism potential of co-enzyme Q10 and co-enzyme Q10/levodopa-carbidopa combination in mice
OJ Onaolapo, AO Odeniyi, SO Jonathan… - Current Aging …, 2021 - ingentaconnect.com
Background: Despite decades of research, neurodegenerative disorders like Parkinson's
disease remain a leading cause of disability worldwide, due to the insufficient reduction of …
disease remain a leading cause of disability worldwide, due to the insufficient reduction of …