Identification of inflammatory mediators and their modulation by strategies for the management of the systemic inflammatory response during cardiac surgery

R Hall - Journal of Cardiothoracic and Vascular Anesthesia, 2013 - jcvaonline.com
THE SYSTEMIC INFLAMMATORY RESPONSE (man-ifested by pyrexia, leukocytosis,
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …

Minimizing systemic inflammation during cardiopulmonary bypass in the pediatric population

Y Durandy - Artificial organs, 2014 - Wiley Online Library
Cardiopulmonary bypass (CPB) is known to cause a systemic inflammatory response.
Inflammation includes several cascade activations: complement, cytokine, and coagulation …

The use of an acellular oxygen carrier in a human liver model of normothermic machine perfusion

RW Laing, RH Bhogal, L Wallace, Y Boteon… - …, 2017 - journals.lww.com
Background Normothermic machine perfusion of the liver (NMP-L) is a novel technique that
preserves liver grafts under near-physiological conditions while maintaining their normal …

Renal protection against ischemia reperfusion injury: hemoglobin-based oxygen carrier-201 versus blood as an oxygen carrier in ex vivo subnormothermic machine …

RN Bhattacharjee, SVB Patel, Q Sun, L Jiang… - …, 2020 - journals.lww.com
Background. The optimal method of oxygen delivery to donor kidneys during ex vivo
machine perfusion has not been established. We have recently reported the beneficial …

[HTML][HTML] Synthetic hemoglobin-based oxygen carriers are an acceptable alternative for packed red blood cells in normothermic kidney perfusion

MM Aburawi, FM Fontan, N Karimian, C Eymard… - American Journal of …, 2019 - Elsevier
Normothermic machine perfusion presents a novel platform for pretransplant assessment
and reconditioning of kidney grafts. Maintaining the metabolic activity of a preserved graft at …

The impact of oxygen supply and erythrocytes during normothermic kidney perfusion

C von Horn, H Zlatev, B Lüer, L Malkus, S Ting… - Scientific Reports, 2023 - nature.com
The influence of erythrocytes and oxygen concentration on kidneys during long-term
normothermic kidney perfusion is under debate. This study compares acellular and …

Elevated levels of procalcitonin and interleukin-6 are linked with postoperative complications in cardiac surgery

A Brocca, GM Virzì, M de Cal… - … Journal of Surgery, 2017 - journals.sagepub.com
Background: Cardiac surgery–associated acute kidney injury is a frequent and serious
postoperative complication of cardiac surgery and is associated with an increased risk of …

Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung: a case control study

PR Tuinman, AP Vlaar, AD Cornet, JJ Hofstra, M Levi… - Critical Care, 2011 - Springer
Introduction Blood transfusion is associated with increased morbidity and mortality in cardiac
surgery patients, but cause-and-effect relations remain unknown. We hypothesized that …

Effects of SDF-1/CXCR4 on acute lung injury induced by cardiopulmonary bypass

H Shi, R Lu, S Wang, H Chen, F Wang, K Liu - Inflammation, 2017 - Springer
Acute lung injury (ALI) is one of the most important complications after cardiopulmonary
bypass (CPB) and the complex pathophysiology remains to be resolved incomplete. SDF …

Readmission to the intensive care unit after fast-track cardiac surgery: an analysis of risk factors and outcome according to the type of operation

F Toraman, S Senay, U Gullu… - The Heart Surgery …, 2010 - journal.hsforum.com
Introduction: In the present study, we investigated risk factors for intensive care unit (ICU)
readmission after fasttrack cardiac surgery and analyzed outcome data according to the type …