Making the invisible visible—ultrashort echo time magnetic resonance imaging: technical developments and applications

Y Ma, H Jang, S Jerban, EY Chang, CB Chung… - Applied Physics …, 2022 - pubs.aip.org
Magnetic resonance imaging (MRI) uses a large magnetic field and radio waves to generate
images of tissues in the body. Conventional MRI techniques have been developed to image …

So you want to image myelin using MRI: an overview and practical guide for myelin water imaging

J Lee, JW Hyun, J Lee, EJ Choi… - Journal of Magnetic …, 2021 - Wiley Online Library
Myelin water imaging (MWI) is an MRI imaging biomarker for myelin. This method can
generate an in vivo whole‐brain myelin water fraction map in approximately 10 minutes. It …

Myelin imaging in human brain using a short repetition time adiabatic inversion recovery prepared ultrashort echo time (STAIR-UTE) MRI sequence in multiple …

YJ Ma, H Jang, Z Wei, Z Cai, Y Xue, RR Lee, EY Chang… - Radiology, 2020 - pubs.rsna.org
Background Water signal contamination is a major challenge for direct ultrashort echo time
(UTE) imaging of myelin in vivo because water contributes most of the signals detected in …

Short-T2 MRI: Principles and recent advances

M Weiger, KP Pruessmann - Progress in nuclear magnetic resonance …, 2019 - Elsevier
Among current modalities of biomedical and diagnostic imaging, MRI stands out by virtue of
its versatile contrast obtained without ionizing radiation. However, in various cases, eg …

Whole-brain myelin imaging using 3D double-echo sliding inversion recovery ultrashort echo time (DESIRE UTE) MRI

YJ Ma, AC Searleman, H Jang, J Wong, EY Chang… - Radiology, 2020 - pubs.rsna.org
Background Signal contamination from long T2 water is a major challenge in direct imaging
of myelin with MRI. Nulling of the unwanted long T2 signals can be achieved with an …

[HTML][HTML] Advances in MRI of the myelin bilayer

M Weiger, R Froidevaux, EL Baadsvik, DO Brunner… - Neuroimage, 2020 - Elsevier
Myelin plays a key role in the function of the central nervous system and is involved in many
neurodegenerative diseases. Hence, depiction of myelin is desired for both research and …

Understanding aqueous and non-aqueous proton T1 relaxation in brain

AP Manning, AL MacKay, CA Michal - Journal of Magnetic Resonance, 2021 - Elsevier
A full picture of longitudinal relaxation in complex heterogeneous environments like white
matter brain tissue remains elusive. In tissue, successive approximations, from the solvation …

Ultra‐short T2 components imaging of the whole brain using 3D dual‐echo UTE MRI with rosette k‐space pattern

X Shen, AC Özen, A Sunjar, S Ilbey… - Magnetic resonance …, 2023 - Wiley Online Library
Purpose This study aimed to develop a new 3D dual‐echo rosette k‐space trajectory,
specifically designed for UTE MRI applications. The imaging of the ultra‐short transverse …

In-situ quantification of lipids in live cells through imaging approaches

Y Hu, RQ Zhang, SL Liu, ZG Wang - Biosensors and Bioelectronics, 2023 - Elsevier
Lipids are important molecules that are widely distributed within the cell, and they play a
crucial role in several biological processes such as cell membrane formation, signaling, cell …

Mapping the myelin bilayer with short‐T2 MRI: Methods validation and reference data for healthy human brain

EL Baadsvik, M Weiger, R Froidevaux… - Magnetic …, 2023 - Wiley Online Library
Purpose To explore the properties of short‐T2 signals in human brain, investigate the impact
of various experimental procedures on these properties and evaluate the performance of …