Obesity and cancer risk: Emerging biological mechanisms and perspectives

KI Avgerinos, N Spyrou, CS Mantzoros, M Dalamaga - Metabolism, 2019 - Elsevier
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

Advances in the prevention and treatment of obesity-driven effects in breast cancers

K Chen, J Zhang, NM Beeraka, C Tang… - Frontiers in …, 2022 - frontiersin.org
Obesity and associated chronic inflammation were shown to facilitate breast cancer (BC)
growth and metastasis. Leptin, adiponectin, estrogen, and several pro-inflammatory …

Cancer and the microbiota

WS Garrett - Science, 2015 - science.org
A host's microbiota may increase, diminish, or have no effect at all on cancer susceptibility.
Assigning causal roles in cancer to specific microbes and microbiotas, unraveling host …

Biological and nutritional properties of palm oil and palmitic acid: effects on health

A Mancini, E Imperlini, E Nigro, C Montagnese… - Molecules, 2015 - mdpi.com
A growing body of evidence highlights the close association between nutrition and human
health. Fat is an essential macronutrient, and vegetable oils, such as palm oil, are widely …

Endocrine disruptors and obesity

PD Darbre - Current obesity reports, 2017 - Springer
Abstract Purpose of Review The purpose of this review was to summarise current evidence
that some environmental chemicals may be able to interfere in the endocrine regulation of …

Microbiota, inflammation and colorectal cancer

C Lucas, N Barnich, HTT Nguyen - International journal of molecular …, 2017 - mdpi.com
Colorectal cancer, the fourth leading cause of cancer-related death worldwide, is a
multifactorial disease involving genetic, environmental and lifestyle risk factors. In addition …

Dietary emulsifier–induced low-grade inflammation promotes colon carcinogenesis

E Viennois, D Merlin, AT Gewirtz, B Chassaing - Cancer research, 2017 - AACR
The increased risks conferred by inflammatory bowel disease (IBD) to the development of
colorectal cancer gave rise to the term “colitis-associated cancer” and the concept that …

Gut dysbiosis: a potential link between increased cancer risk in ageing and inflammaging

A Biragyn, L Ferrucci - The Lancet Oncology, 2018 - thelancet.com
Cancer incidence substantially increases with ageing in both men and women, although the
reason for this increase is unknown. In this Series paper, we propose that age-associated …

Water a major source of endocrine-disrupting chemicals: An overview on the occurrence, implications on human health and bioremediation strategies

A Thacharodi, S Hassan, TA Hegde… - Environmental …, 2023 - Elsevier
Endocrine disrupting chemicals (EDCs) are toxic compounds that occur naturally or are the
output of anthropogenic activities that negatively impact both humans and wildlife. A number …

The effect of ketogenic diet on shared risk factors of cardiovascular disease and cancer

N Mohammadifard, F Haghighatdoost, M Rahimlou… - Nutrients, 2022 - mdpi.com
Cardiovascular disease (CVD) and cancer are the first and second leading causes of death
worldwide, respectively. Epidemiological evidence has demonstrated that the incidence of …