[HTML][HTML] Long-term potentiation and memory

MA Lynch - Physiological reviews, 2004 - journals.physiology.org
Abstract Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004;
10.1152/physrev. 00014.2003.—One of the most significant challenges in neuroscience is to …

[HTML][HTML] The functional organization of the barrel cortex

CCH Petersen - Neuron, 2007 - cell.com
The tactile somatosensory pathway from whisker to cortex in rodents provides a well-defined
system for exploring the link between molecular mechanisms, synaptic circuits, and …

Spatiotemporal Rescue of Memory Dysfunction in Drosophila

SE McGuire, PT Le, AJ Osborn, K Matsumoto, RL Davis - Science, 2003 - science.org
We have developed a method for temporal and regional gene expression targeting
(TARGET) in Drosophila and show the simultaneous spatial and temporal rescue of a …

Development and critical period plasticity of the barrel cortex

RS Erzurumlu, P Gaspar - European Journal of Neuroscience, 2012 - Wiley Online Library
In primary sensory neocortical areas of mammals, the distribution of sensory receptors is
mapped with topographic precision and amplification in proportion to the peripheral receptor …

International union of basic and clinical pharmacology. CI. Structures and small molecule modulators of mammalian adenylyl cyclases

CW Dessauer, VJ Watts, RS Ostrom, M Conti… - Pharmacological …, 2017 - Elsevier
Adenylyl cyclases (ACs) generate the second messenger cAMP from ATP. Mammalian cells
express nine transmembrane AC (mAC) isoforms (AC1–9) and a soluble AC (sAC, also …

Regulation and role of adenylyl cyclase isoforms

J Hanoune, N Defer - Annual review of pharmacology and …, 2001 - annualreviews.org
At least nine closely related isoforms of adenylyl cyclases (ACs), the enzymes responsible
for the synthesis of cyclic AMP (cAMP) from ATP, have been cloned and characterized in …

PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis

S Seino, T Shibasaki - Physiological reviews, 2005 - journals.physiology.org
Stimulus-secretion coupling is an essential process in secretory cells in which regulated
exocytosis occurs, including neuronal, neuroendocrine, endocrine, and exocrine cells. While …

Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies

R Sadana, CW Dessauer - Neurosignals, 2009 - karger.com
Cyclic AMP is a universal second messenger, produced by a family of adenylyl cyclase (AC)
enzymes. The last three decades have brought a wealth of new information about the …

Physiological roles of mammalian transmembrane adenylyl cyclase isoforms

KF Ostrom, JE LaVigne, TF Brust… - Physiological …, 2022 - journals.physiology.org
Adenylyl cyclases (ACs) catalyze the conversion of ATP to the ubiquitous second
messenger cAMP. Mammals possess nine isoforms of transmembrane ACs, dubbed AC1–9 …

[HTML][HTML] Isoforms of mammalian adenylyl cyclase: multiplicities of signaling

RK Sunahara, R Taussig - Molecular interventions, 2002 - triggered.edina.clockss.org
Mechanistic descriptions of cAMP production have evolved significantly since the 1960s
when Sutherland and Rall hypothesized the existence of a single polypeptide that would …