The Deuterated “Magic Methyl” Group: A Guide to Site‐Selective Trideuteromethyl Incorporation and Labeling by Using CD3 Reagents
J Steverlynck, R Sitdikov… - Chemistry–A European …, 2021 - Wiley Online Library
In the field of medicinal chemistry, the precise installation of a trideuteromethyl group is
gaining ever‐increasing attention. Site‐selective incorporation of the deuterated “magic …
gaining ever‐increasing attention. Site‐selective incorporation of the deuterated “magic …
Alcohols as Substrates in Transition-Metal-Catalyzed Arylation, Alkylation, and Related Reactions
Alcohols are abundant and attractive feedstock molecules for organic synthesis. Many
methods for their functionalization require them to first be converted into a more activated …
methods for their functionalization require them to first be converted into a more activated …
Manganese-catalyzed β-alkylation of secondary alcohols with primary alcohols under phosphine-free conditions
T Liu, L Wang, K Wu, Z Yu - ACS Catalysis, 2018 - ACS Publications
Manganese (I) complexes bearing a pyridyl-supported pyrazolyl-imidazolyl ligand efficiently
catalyzed the direct β-alkylation of secondary alcohols with primary alcohols under …
catalyzed the direct β-alkylation of secondary alcohols with primary alcohols under …
Divergent Synthesis of Alcohols and Ketones via Cross‐Coupling of Secondary Alcohols under Manganese Catalysis
A homogeneous manganese‐catalyzed cross‐coupling of two secondary alcohols for the
divergent synthesis of γ‐disubstituted alcohols and β‐disubstituted ketones is reported …
divergent synthesis of γ‐disubstituted alcohols and β‐disubstituted ketones is reported …
Well-Defined Phosphine-Free Iron-Catalyzed N-Ethylation and N-Methylation of Amines with Ethanol and Methanol
An iron (0) complex bearing a cyclopentadienone ligand catalyzed N-methylation and N-
ethylation of aryl and aliphatic amines with methanol or ethanol in mild and basic conditions …
ethylation of aryl and aliphatic amines with methanol or ethanol in mild and basic conditions …
Manganese‐Catalyzed Chemoselective Coupling of Secondary Alcohols, Primary Alcohols and Methanol
J Tang, J He, SY Zhao, W Liu - … Chemie International Edition, 2023 - Wiley Online Library
Herein, we report a manganese‐catalyzed three‐component coupling of secondary
alcohols, primary alcohols and methanol for the synthesis of β, β‐methylated/alkylated …
alcohols, primary alcohols and methanol for the synthesis of β, β‐methylated/alkylated …
Nickel-Catalyzed Guerbet Type Reaction: C-Alkylation of Secondary Alcohols via Double (de)Hydrogenation
R Babu, M Subaramanian, SP Midya… - Organic Letters, 2021 - ACS Publications
Acceptorless double dehydrogenative cross-coupling of secondary and primary alcohols
under nickel catalysis is reported. This Guerbet type reaction provides an atom-and a step …
under nickel catalysis is reported. This Guerbet type reaction provides an atom-and a step …
Ruthenium (II) complexes of heteroditopic N-heterocyclic carbene ligands: efficient catalysts for C–N bond formation via a hydrogen-borrowing strategy under solvent …
Both imidazol-2-ylidene (ImNHC) and 1, 2, 3-triazol-5-ylidene (tzNHC) have evolved to be
elite groups of N-heterocyclic carbene (NHC) ligands for homogeneous catalysis. To …
elite groups of N-heterocyclic carbene (NHC) ligands for homogeneous catalysis. To …
Selective catalytic synthesis of α-alkylated ketones and β-disubstituted ketones via acceptorless dehydrogenative cross-coupling of alcohols
Herein, a phosphine-free pincer ruthenium (III) catalyzed β-alkylation of secondary alcohols
with primary alcohols to α-alkylated ketones and two different secondary alcohols to β …
with primary alcohols to α-alkylated ketones and two different secondary alcohols to β …
Catalytic cross-coupling of secondary alcohols
S Thiyagarajan, C Gunanathan - Journal of the American …, 2019 - ACS Publications
Herein, an unprecedented ruthenium (II) catalyzed direct cross-coupling of two different
secondary alcohols to β-disubstituted ketones is reported. Cyclic, acylic, symmetrical, and …
secondary alcohols to β-disubstituted ketones is reported. Cyclic, acylic, symmetrical, and …