During recent decades vast and continuously increasing numbers of biomedical implants
have been introduced for continuous use in the human body. Since the early cemented hip …

Cells in their in vivo microenvironment constantly encounter and respond to a multitude of
signals. While the role of biochemical signals has long been appreciated, the importance of …

The osseointegration rate of titanium dental implants is related to their composition and
surface roughness. Rough-surfaced implants favor both bone anchoring and biomechanical …

Osteoblast cell adhesion is the initial step of early osseointegration responding to bone
material implants. Enhancing the osteoblastic cell adhesion has become one of the prime …

The urge to replace missing teeth dates back to the origin of medicine. Along history, organic
materials, metals, alloys, polymers, glasses, and carbon were used to substitute teeth, but …

Long-term clinical success of endosseous dental implants is critically related to a wide bone-
to-implant direct contact. This condition is called osseointegration and is achieved ensuring …

Classically various treatments are applied to increase the roughness of titanium implants
and improve their integration in the tissues. Many in vitro studies have been performed to …

The surface roughness of metallic orthopaedic implants has typically been used to influence
osseointegration and spatially control load transfer to the surrounding bone. Because of the …

A high-throughput method for analyzing cellular response to crystallinity in a polymer
material is presented. Variations in crystallinity lead to changes in surface roughness on …

A current medical challenge is the replacement of tissue which can be thought of in terms of
bone tissue engineering approaches. The key problem in bone tissue engineering lies in …