Notch and vascular smooth muscle cell phenotype

D Morrow, S Guha, C Sweeney, Y Birney… - Circulation …, 2008 - Am Heart Assoc
The Notch signaling pathway is critical for cell fate determination during embryonic
development, including many aspects of vascular development. An emerging paradigm …

MicroRNA-145 in vascular smooth muscle cell biology: a new therapeutic target for vascular disease

C Zhang - Cell Cycle, 2009 - Taylor & Francis
Vascular smooth muscle cell (VSMC) phenotypic modulation and proliferation are critical
cellular events in the development of a variety of proliferative vascular diseases. However …

MicroRNA‐26a is a novel regulator of vascular smooth muscle cell function

NJ Leeper, A Raiesdana, Y Kojima… - Journal of cellular …, 2011 - Wiley Online Library
Aberrant smooth muscle cell (SMC) plasticity has been implicated in a variety of vascular
disorders including atherosclerosis, restenosis, and abdominal aortic aneurysm (AAA) …

Biodegradable PAMAM ester for enhanced transfection efficiency with low cytotoxicity

HY Nam, K Nam, HJ Hahn, BH Kim, HJ Lim, HJ Kim… - Biomaterials, 2009 - Elsevier
We synthesized biodegradable polycationic PAMAM (polyamidoamine) esters (e-PAM-R, e-
PAM-K) that contain arginines or lysines at the peripheral ends of PAMAM–OH dendrimer …

Salusin-β Promotes Vascular Smooth Muscle Cell Migration and Intimal Hyperplasia After Vascular Injury via ROS/NFκB/MMP-9 Pathway

HJ Sun, MX Zhao, XS Ren, TY Liu, Q Chen… - Antioxidants & Redox …, 2016 - liebertpub.com
Aims: Media-to-intima migration of vascular smooth muscle cells (VSMCs) is critical to
intimal thickening in atherosclerosis and restenosis after coronary angioplasty. The aim of …

CB2 cannabinoid receptor agonists attenuate TNF‐α‐induced human vascular smooth muscle cell proliferation and migration

M Rajesh, P Mukhopadhyay, G Hasko… - British journal of …, 2008 - Wiley Online Library
Background and purpose: Vascular smooth muscle proliferation and migration triggered by
inflammatory stimuli are involved in the development and progression of atherosclerosis and …

Exosome-mediated transfer of ACE (angiotensin-converting enzyme) from adventitial fibroblasts of spontaneously hypertensive rats promotes vascular smooth muscle …

Y Tong, C Ye, XS Ren, Y Qiu, YH Zang, XQ Xiong… - …, 2018 - Am Heart Assoc
Migration of vascular smooth muscle cells (VSMCs) is pivotal for vascular remodeling in
hypertension. Vascular adventitial fibroblasts (AFs) are important in the homeostasis of …

Roles of exosomal miRNA in vascular aging

S Du, H Ling, Z Guo, Q Cao, C Song - Pharmacological Research, 2021 - Elsevier
Aging is a major risk factor for human diseases. As global average life expectancy has
lengthened, delaying or reducing aging and age-related diseases has become an urgent …

Curcumin attenuates migration of vascular smooth muscle cells via inhibiting NFκB-mediated NLRP3 expression in spontaneously hypertensive rats

Y Han, HJ Sun, Y Tong, YZ Chen, C Ye, Y Qiu… - The Journal of …, 2019 - Elsevier
Migration of vascular smooth muscle cell (VSMC) plays a critical role in the pathophysiology
of hypertension and several other vascular diseases. Curcumin (1, 7-bis (4-hydroxy-3 …

Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein …

N Begum, S Hockman, VC Manganiello - Journal of Biological Chemistry, 2011 - ASBMB
Cyclic nucleotide phosphodiesterase 3 (PDE3) is an important regulator of cyclic adenosine
monophosphate (cAMP) signaling within the cardiovascular system. In this study, we …