The biological activity and structural diversity of natural products are unsurpassed by any
available synthetic screening libraries. As such, these privileged scaffolds serve as …

Oridonin, as a natural terpenoids found in traditional Chinese herbal medicine Isodon
rubescens (Hemsl.) H. Hara, is widely present in numerous Chinese medicine preparations …

Cancer is one of the diseases with high morbidity and mortality on a global scale.
Chemotherapy remains the primary treatment option for most cancer patients, including …

Cancer is a leading cause of morbidity and mortality worldwide. Apoptosis is a process of
programmed cell death and it plays a vital role in human development and tissue …

Inflammation plays a pivotal role in the development and progression of diabetic
nephropathy (DN). Oridonin (Ori), a component isolated from Rabdosia rubescens …

Oridonin, an active diterpenoid isolated from Rabdosia rubescens, has been reported for its
antitumor activity on several cancers. However, its effect on human esophageal cancer …

Oridonin belongs to ent-kaurane tetracyclic diterpenoid and was first isolated from Isodon
species. It exhibits inhibitory activities against a variety of tumor cells, and pharmacological …

Cancer is a leading cause of mortality worldwide, and its incidence is rapidly growing over
the years. In 2020, there were an estimated 10 million cancer deaths and 19.3 million new …

Abstract Context: Methicillin-resistant Staphylococcus aureus (MRSA) is a very harmful
bacterium. Oridonin, a component in Rabdosia rubescens (Hemsl.) Hara (Lamiaceae), is …

The biological function of the natural ent-kaurene diterpenoid isolated from genus Isodon,
oridonin, has been intensively studied. However, its mechanism studies and clinical …