Post-translational modifications in oral bacteria and their functional impact

Q Ma, Q Zhang, Y Chen, S Yu, J Huang, Y Liu… - Frontiers in …, 2021 - frontiersin.org
Oral bacteria colonize the oral cavity, surrounding complex and variable environments. Post-
translational modifications (PTMs) are an efficient biochemical mechanism across all …

Aspects of oral streptococcal metabolic diversity: Imagining the landscape beneath the fog

P Zuber, J Kreth - Molecular Microbiology, 2023 - Wiley Online Library
It is widely acknowledged that the human‐associated microbial community influences host
physiology, systemic health, disease progression, and even behavior. There is currently an …

The vicK gene of Streptococcus mutans mediates its cariogenicity via exopolysaccharides metabolism

Y Deng, Y Yang, B Zhang, H Chen, Y Lu… - International Journal of …, 2021 - nature.com
Streptococcus mutans (S. mutans) is generally regarded as a major contributor to dental
caries because of its ability to synthesize extracellular polysaccharides (EPS) that aid in the …

Inhibitory Effect of Adsorption of Streptococcus mutans onto Scallop-Derived Hydroxyapatite

M Usuda, M Kametani, M Hamada, Y Suehiro… - International journal of …, 2023 - mdpi.com
Hydroxyapatite adsorbs various substances, but little is known about the effects on oral
bacteria of adsorption onto hydroxyapatite derived from scallop shells. In the present study …

CodY is modulated by YycF and affects biofilm formation in Staphylococcus aureus

S Wu, B Qin, S Deng, Y Liu, H Zhang, L Lei… - Frontiers in …, 2022 - frontiersin.org
Background Staphylococcus aureus (S. aureus) is the leading cause of various infective
diseases, including topical soft tissue infections. The goals of this study were to investigate …

Antibacterial Activity of a Lysin LysP53 against Streptococcus mutans

X Zhao, C Li, H Yang, H Wei… - Journal of Dental …, 2023 - journals.sagepub.com
Dental caries is a common disease affecting quality of life globally. In the present study, we
found that a bacteriophage lysin LysP53 against Acinetobacter baumannii possesses …

vicR overexpression in Streptococcus mutans causes aggregation and affects interspecies competition

J Yan, T Gong, Q Ma, T Zheng, J Chen… - Molecular Oral …, 2023 - Wiley Online Library
Streptococcus mutans is considered to be a major causative agent of dental caries. VicRK is
a two‐component signal transduction system (TCSTS) of S. mutans, which can regulate the …

Systematic analysis of lysine malonylation in Streptococcus mutans

Z Li, Q Wu, Y Zhang, X Zhou, X Peng - Frontiers in Cellular and …, 2022 - frontiersin.org
Protein lysine malonylation (Kmal) is a novel post-translational modification (PTM) that
regulates various biological pathways such as energy metabolism and translation …

VicRK and CovR polymorphisms in Streptococcus mutans strains associated with cardiovascular infections

LT Oliveira, LA Alves, EN Harth-Chu… - Journal of medical …, 2021 - microbiologyresearch.org
Introduction. Streptococcus mutans, a common species of the oral microbiome, expresses
virulence genes promoting cariogenic dental biofilms, persistence in the bloodstream and …

Druggable sites identification in Streptococcus mutans VicRK system evaluated by catechols

P Henrique Santana Silveira… - Journal of Biomolecular …, 2023 - Taylor & Francis
Dental caries is a global public health problem, being the most common non-communicable
disease. Streptococcus mutans, the causative agent of human cariogenic dental biofilms …