Tools and strategies of systems metabolic engineering for the development of microbial cell factories for chemical production

YS Ko, JW Kim, JA Lee, T Han, GB Kim… - Chemical Society …, 2020 - pubs.rsc.org
Sustainable production of chemicals from renewable non-food biomass has become a
promising alternative to overcome environmental issues caused by our heavy dependence …

The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology

TE Sandberg, MJ Salazar, LL Weng, BO Palsson… - Metabolic …, 2019 - Elsevier
Harnessing the process of natural selection to obtain and understand new microbial
phenotypes has become increasingly possible due to advances in culturing techniques …

A comprehensive metabolic map for production of bio-based chemicals

SY Lee, HU Kim, TU Chae, JS Cho, JW Kim, JH Shin… - Nature …, 2019 - nature.com
Production of industrial chemicals using renewable biomass feedstock is becoming
increasingly important to address limited fossil resources, climate change and other …

Designing microbial cell factories for the production of chemicals

JS Cho, GB Kim, H Eun, CW Moon, SY Lee - Jacs Au, 2022 - ACS Publications
The sustainable production of chemicals from renewable, nonedible biomass has emerged
as an essential alternative to address pressing environmental issues arising from our heavy …

High-throughput screening technology in industrial biotechnology

W Zeng, L Guo, S Xu, J Chen, J Zhou - Trends in biotechnology, 2020 - cell.com
Based on the development of automatic devices and rapid assay methods, various high-
throughput screening (HTS) strategies have been established for improving the performance …

[HTML][HTML] Engineering cellular metabolism

J Nielsen, JD Keasling - Cell, 2016 - cell.com
Metabolic engineering is the science of rewiring the metabolism of cells to enhance
production of native metabolites or to endow cells with the ability to produce new products …

[HTML][HTML] Pseudomonas putida as a functional chassis for industrial biocatalysis: from native biochemistry to trans-metabolism

PI Nikel, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
The itinerary followed by Pseudomonas putida from being a soil-dweller and plant colonizer
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …

[HTML][HTML] An overview of potential oleaginous microorganisms and their role in biodiesel and omega-3 fatty acid-based industries

A Patel, D Karageorgou, E Rova, P Katapodis, U Rova… - Microorganisms, 2020 - mdpi.com
Microorganisms are known to be natural oil producers in their cellular compartments.
Microorganisms that accumulate more than 20% w/w of lipids on a cell dry weight basis are …

Metabolic burden: cornerstones in synthetic biology and metabolic engineering applications

G Wu, Q Yan, JA Jones, YJ Tang, SS Fong… - Trends in …, 2016 - cell.com
Engineering cell metabolism for bioproduction not only consumes building blocks and
energy molecules (eg, ATP) but also triggers energetic inefficiency inside the cell. The …

[图书][B] Aplicando a quarta revolução industrial

K Schwab, N Davis - 2019 - books.google.com
A nova revolução tecnológica está reformulando a economia global e as sociedades como
um todo. Os sistemas que hoje aceitamos como certos, desde o modo como produzimos e …