Organocatalytic Friedel–Crafts arylation of aldehydes with indoles utilizing N-heterocyclic iod (az) olium salts as halogen-bonding catalysts

EM Galathri, TJ Kuczmera, BJ Nachtsheim… - Green …, 2024 - pubs.rsc.org
The Friedel–Crafts arylation is among the most known organic reactions, usually being
promoted by a Lewis acid, that have been employed for the synthesis of bis-indolyl …

Friedel–Crafts arylation of aldehydes with indoles utilizing arylazo sulfones as the photoacid generator

LD Terlizzi - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
A versatile, inexpensive and sustainable protocol for the preparation of valuable bis-indolyl
methanes via visible light-mediated, metal-free Friedel–Crafts arylation has been …

FeCl3·6H2O as a Mild Catalyst for Nucleophilic Substitution of Symmetrical Bis(indoyl)methanes

C Chantana, J Jaratjaroonphong - The Journal of Organic …, 2021 - ACS Publications
In this paper, unsymmetrical bis (indolyl) methane (BIM) and 3-alkylindole derivatives are
smoothly synthesized from symmetrical BIMs with a variety of nucleophiles including …

Expedient Access to Indolyl-Substituted Tri-and Diarylmethanes and (±)-Colletotryptin E by Silica Sulfuric Acid Catalyzed Transindolylation

J Yimyaem, C Chantana, S Boonmee… - Synlett, 2022 - thieme-connect.com
An expedient access to a series of nonsymmetrical bis (indolyl) methanes (BIMs) through
transindolylation of readily available symmetrical 3, 3′-BIMs with various indoles catalyzed …

Effect of N-heterocyclic carbene in palladium–tin heterobimetallic catalysis: a DFT supported study on the C3–H functionalization of unprotected indoles

MK Nayak, RR Maharana, A Mohanty… - Catalysis Science & …, 2024 - pubs.rsc.org
A new N-heterocyclic carbene (NHC)-based Pd–Sn heterobimetallic complex [(NHC) Pd (μ-
Br) SnCl3] 2 with low steric crowding in the active catalytic region was designed. The …

Azobenzene derivatives of 3, 3'-bis (indolyl) methanes: Novel electroactive materials with antioxidant activities

P Sivaguru, N Sedhu, A Lalitha - Synthetic Metals, 2023 - Elsevier
A practical and efficient synthesis of new electroactive azobenzene derivatives of bis
(indolyl) methanes has been achieved via the Friedel-Crafts reaction of indole with 5 …

Developing a highly potent anthelmintic: study of catalytic application of l-proline derived aminothiourea in rapid synthesis of biscoumarins and their in vitro …

B Kharrngi, ED Dhar, G Basumatary, D Das… - Journal of Chemical …, 2021 - Springer
Due to serious side effects of benzimidazoles such as apoptosis and mitotic arrest,
development of alternative anthelmintic drugs with comparable efficacy to target the …

Green and sustainable approaches for the Friedel–Crafts reaction between aldehydes and indoles

PX Kolagkis, EM Galathri… - Beilstein Journal of …, 2024 - beilstein-journals.org
The synthesis of indoles and their derivatives, more specifically bis (indolyl) methanes
(BIMs), has been an area of great interest in organic chemistry, since these compounds …

Thermally Activated Aryl Thioureas as Brønsted Acid Catalysts for C–C Bond Forming Reactions: Synthesis of Symmetrical Trisubstituted Methanes

A Gogoi, G Basumatary, G Bez - Synthesis, 2023 - thieme-connect.com
A study on relative catalytic efficacy of 1, 3-diaryl thioureas has revealed that 1-[3, 5-bis
(trifluoromethyl) phenyl]-3-phenylthiourea is an efficient alternative to the Schreiner's …

L-proline H2SO4 catalyzed synthesis of novel coumarin-based spiroindolino-3,4-dihydropyrimidin-2(1H)-ones: in vitro cytotoxic assay and molecular docking study

Mezhubeinuo, R Mohanta, H Bordoloi, AK Verma… - Molecular Diversity, 2024 - Springer
Abstract Development of environmentally benign catalyst systems, especially those derived
from readily available nature's pool, in multicomponent synthesis, consolidates multiple …