The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

The targeted and efficiency-oriented delivery of (therapeutic) nucleic acids raises hope for
successful gene therapy, ie, for the local and individual treatment of acquired and inherited …

Gold nanoparticles provide an attractive and applicable scaffold for delivery of nucleic acids.
In this review, we focus on the use of covalent and noncovalent gold nanoparticle …

Chemotherapeutic agents have certain limitations when it comes to treating cancer, the most
important being severe side effects along with multidrug resistance developed against them …

A lipid coated calcium phosphate (LCP) nanoparticle (NP) formulation was developed for
efficient delivery of small interfering RNA (siRNA) to a xenograft tumor model by intravenous …

For the longest time, the field of nucleic acid delivery has remained skeptical whether or not
polycationic drug carrier systems would ever make it into clinical practice. Yet, with the …

Introduction Gene therapy is a promising approach to be applied in cardiac regeneration
after myocardial infarction and gene correction for inherited cardiomyopathies. However …

Nanoparticles (NPs) can serve as a promising vaccine delivery platform for improving
pharmacological property and codelivery of antigens and adjuvants. However, NP‐based …

Highlights•Minor modifications to polymer structure determine transfection
properties.•Efficient gene delivery requires timely release of DNA.•Serum stability is …