The molecular basis of heterochromatin assembly and epigenetic inheritance
SIS Grewal - Molecular cell, 2023 - cell.com
Heterochromatin plays a fundamental role in gene regulation, genome integrity, and
silencing of repetitive DNA elements. Histone modifications are essential for the …
silencing of repetitive DNA elements. Histone modifications are essential for the …
The expanding world of small RNAs in plants
F Borges, RA Martienssen - Nature reviews Molecular cell biology, 2015 - nature.com
Plant genomes encode various small RNAs that function in distinct, yet overlapping, genetic
and epigenetic silencing pathways. However, the abundance and diversity of small-RNA …
and epigenetic silencing pathways. However, the abundance and diversity of small-RNA …
Taming transposable elements in vertebrates: from epigenetic silencing to domestication
Transposable element (TE)-derived sequences are ubiquitous in most eukaryotic genomes
known to date. Because their expression and mobility can lead to genomic instability …
known to date. Because their expression and mobility can lead to genomic instability …
Transgenerational epigenetic inheritance
A Bošković, OJ Rando - Annual review of genetics, 2018 - annualreviews.org
Inheritance of genomic DNA underlies the vast majority of biological inheritance, yet it has
been clear for decades that additional epigenetic information can be passed on to future …
been clear for decades that additional epigenetic information can be passed on to future …
Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence …
G Janbon, KL Ormerod, D Paulet, EJ Byrnes III… - PLoS …, 2014 - journals.plos.org
Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …
Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA: DNA hybrid formation
O Velazquez Camacho, C Galan, K Swist-Rosowska… - Elife, 2017 - elifesciences.org
The Suv39h1 and Suv39h2 histone lysine methyltransferases are hallmark enzymes at
mammalian heterochromatin. We show here that the mouse Suv39h2 enzyme differs from …
mammalian heterochromatin. We show here that the mouse Suv39h2 enzyme differs from …
Kinetic competition during the transcription cycle results in stochastic RNA processing
A Coulon, ML Ferguson, V de Turris, M Palangat… - Elife, 2014 - elifesciences.org
Synthesis of mRNA in eukaryotes involves the coordinated action of many enzymatic
processes, including initiation, elongation, splicing, and cleavage. Kinetic competition …
processes, including initiation, elongation, splicing, and cleavage. Kinetic competition …
Cryptococcus neoformans: historical curiosity to modern pathogen
The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …
stimulated its development as an experimental model for both basic physiology and …
Repeat‐induced point mutation and other genome defense mechanisms in fungi
E Gladyshev - The fungal kingdom, 2017 - Wiley Online Library
Mobile DNA, comprising both active and decaying copies of transposable elements (TEs), is
present in nearly all living organisms. Although fungal genomes tend to be significantly …
present in nearly all living organisms. Although fungal genomes tend to be significantly …
Silencing of active transposable elements in plants
Highlights•Multiple mechanisms exist to repress the mutagenic potential of transposable
element (TE) activity.•Transcriptionally active TEs trigger normally latent pathways including …
element (TE) activity.•Transcriptionally active TEs trigger normally latent pathways including …