Respiratory syncytial virus infection and novel interventions
AC Langedijk, LJ Bont - Nature Reviews Microbiology, 2023 - nature.com
The large global burden of respiratory syncytial virus (RSV) respiratory tract infections in
young children and older adults has gained increased recognition in recent years. Recent …
young children and older adults has gained increased recognition in recent years. Recent …
The road to approved vaccines for respiratory syncytial virus
TJ Ruckwardt - NPJ vaccines, 2023 - nature.com
After decades of work, several interventions to prevent severe respiratory syncytial virus
(RSV) disease in high-risk infant and older adult populations have finally been approved …
(RSV) disease in high-risk infant and older adult populations have finally been approved …
Molecular and phenotypic characteristics of RSV infections in infants during two nirsevimab randomized clinical trials
B Ahani, KM Tuffy, AA Aksyuk, D Wilkins… - Nature …, 2023 - nature.com
Nirsevimab is a monoclonal antibody that binds to the respiratory syncytial virus (RSV)
fusion protein. During the Phase 2b (NCT02878330) and MELODY (NCT03979313) clinical …
fusion protein. During the Phase 2b (NCT02878330) and MELODY (NCT03979313) clinical …
Clinical, genomic, and immunological characterization of RSV surge in Sydney, Australia, 2022
OBJECTIVES The 2022 seasonal respiratory syncytial virus (RSV) epidemic in Sydney,
Australia saw an unprecedented number of RSV detections. We aimed to characterize …
Australia saw an unprecedented number of RSV detections. We aimed to characterize …
[HTML][HTML] Nirsevimab for the prevention of respiratory syncytial virus disease in children. Statement of the Spanish Society of Paediatric Infectious Disease (SEIP)
L Francisco, M Cruz-Canete, C Pérez… - Anales de Pediatría …, 2023 - Elsevier
Introduction Nirsevimab, a monoclonal antibody for the prevention of disease caused by
respiratory syncytial virus (RSV), has recently been approved for use in Europe and Spain …
respiratory syncytial virus (RSV), has recently been approved for use in Europe and Spain …
The respiratory syncytial virus vaccine and monoclonal antibody landscape: the road to global access
Respiratory syncytial virus (RSV) is the second most common pathogen causing infant
mortality. Additionally, RSV is a major cause of morbidity and mortality in older adults (age≥ …
mortality. Additionally, RSV is a major cause of morbidity and mortality in older adults (age≥ …
[HTML][HTML] The path towards effective respiratory syncytial virus immunization policies: recommended actions
F Martinón-Torres, JA Navarro-Alonso… - Archivos de …, 2023 - Elsevier
The respiratory syncytial virus (RSV) causes a substantial burden worldwide. After over six
decades of research, there is finally a licensed immunization option that can protect the …
decades of research, there is finally a licensed immunization option that can protect the …
Current state and challenges in respiratory syncytial virus drug discovery and development
G Zou, S Cao, Z Gao, J Yie, JZ Wu - Antiviral Research, 2023 - Elsevier
Human respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract
infections (LRTI) in young children and elderly people worldwide. Recent significant …
infections (LRTI) in young children and elderly people worldwide. Recent significant …
Systematic Review of the Efficacy and Safety of RSV‐Specific Monoclonal Antibodies and Antivirals in Development
ATK Sevendal, S Hurley, AW Bartlett… - Reviews in Medical …, 2024 - Wiley Online Library
Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infection amongst
all ages, causing a significant global health burden. Preventative and therapeutic options for …
all ages, causing a significant global health burden. Preventative and therapeutic options for …
The beginning of a new era in RSV control
HC Meissner - Pediatrics, 2023 - publications.aap.org
Since the initial isolation in 1956 of what is now identified as respiratory syncytial virus
(RSV), seasonal outbreaks of illness attributable to this enigmatic respiratory virus have …
(RSV), seasonal outbreaks of illness attributable to this enigmatic respiratory virus have …