Importance Acute myocarditis, defined as a sudden inflammatory injury to the myocardium,
affects approximately 4 to 14 people per 100 000 each year globally and is associated with …

Acute rheumatic fever (ARF) is the result of an autoimmune response to pharyngitis caused
by infection with group A Streptococcus. The long-term damage to cardiac valves caused by …

Background Rheumatic heart disease affects more than 40.5 million people worldwide and
results in 306,000 deaths annually. Echocardiographic screening detects rheumatic heart …

Níveis de evidência Nível A Dados obtidos a partir de múltiplos estudos randomizados de
bom porte, concordantes e/ou de meta-análise robusta de estudos clínicos randomizados …

The global burden of rheumatic heart disease continues to be significant although it is
largely limited to poor and marginalized populations. In most endemic regions, affected …

Level of evidence Level A Data obtained from multiple concordant large randomized trials
and/or robust meta-analysis of randomized clinical trials Level B Data obtained from less …

Rheumatic heart disease (RHD) is a preventable heart condition that remains endemic
among vulnerable groups in many countries. After a period of relative neglect, there has …

Acute rheumatic fever is caused by an autoimmune response to throat infection with
Streptococcus pyogenes. Cardiac involvement during acute rheumatic fever can result in …

Rheumatic heart disease (RHD) is an important and preventable cause of morbidity and
mortality among children and young adults in low-income and middle-income countries, as …

Introduction Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) cause
significant morbidity and premature mortality among Australian Aboriginal and Torres Strait …