New perspectives on evolutionary medicine: the relevance of microevolution for human health and disease
FJ Rühli, M Henneberg - BMC medicine, 2013 - Springer
Evolutionary medicine (EM) is a growing field focusing on the evolutionary basis of human
diseases and their changes through time. To date, the majority of EM studies have used …
diseases and their changes through time. To date, the majority of EM studies have used …
Type 1 diabetes prevalence increasing globally and regionally: the role of natural selection and life expectancy at birth
WP You, M Henneberg - BMJ open diabetes research and care, 2016 - drc.bmj.com
Objective: Prevalence of type 1 diabetes (T1D) disease is increasing worldwide. We aim to
test correlation of T1D prevalence to the reduced natural selection measured by Biological …
test correlation of T1D prevalence to the reduced natural selection measured by Biological …
Cancer incidence increasing globally: The role of relaxed natural selection
W You, M Henneberg - Evolutionary applications, 2018 - Wiley Online Library
Cancer incidence increase has multiple aetiologies. Mutant alleles accumulation in
populations may be one of them due to strong heritability of many cancers. The opportunity …
populations may be one of them due to strong heritability of many cancers. The opportunity …
Evolutionary medicine: the ongoing evolution of human physiology and metabolism
F Rühli, K van Schaik, M Henneberg - Physiology, 2016 - journals.physiology.org
The field of evolutionary medicine uses evolutionary principles to understand changes in
human anatomy and physiology that have occurred over time in response to environmental …
human anatomy and physiology that have occurred over time in response to environmental …
Relaxed natural selection contributes to global obesity increase more in males than in females due to more environmental modifications in female body mass
W You, M Henneberg - PloS one, 2018 - journals.plos.org
Objective Relaxed natural selection, measured by Biological State Index (Ibs), results in
unfavourable genes/mutations accumulation in population. Obesity is partly heritable. We …
unfavourable genes/mutations accumulation in population. Obesity is partly heritable. We …
Worldwide increase of obesity is related to the reduced opportunity for natural selection
A Budnik, M Henneberg - PloS one, 2017 - journals.plos.org
Worldwide rise of obesity may be partly related to the relaxation of natural selection in the
last few generations. Accumulation of mutations affecting metabolism towards excessive fat …
last few generations. Accumulation of mutations affecting metabolism towards excessive fat …
Healthcare services relaxing natural selection may contribute to increase of dementia incidence
Ageing and genetic traits can only explain the increasing dementia incidence partially.
Advanced healthcare services allow dementia patients to survive natural selection and pass …
Advanced healthcare services allow dementia patients to survive natural selection and pass …
Anatomical variations and evolution: re‐evaluating their importance for surgeons
A Saniotis, M Henneberg - ANZ Journal of Surgery, 2021 - Wiley Online Library
For several decades, anatomists and biological anthropologists have made an intensive
study in anatomical variations in ancestral and living humans. While many anatomical …
study in anatomical variations in ancestral and living humans. While many anatomical …
Neuro-hormonal regulation is a better indicator of human cognitive abilities than brain anatomy: the need for a new paradigm
Human intelligence has been theorized since the ancient Greeks. Plato and Aristotle
incorporated theories of human intelligence into their metaphysical and cosmological …
incorporated theories of human intelligence into their metaphysical and cosmological …
Increasing variability of body mass and health correlates in Swiss conscripts, a possible role of relaxed natural selection?
Background and objectives The body mass index (BMI) is an established anthropometric
index for the development of obesity-related conditions. However, little is known about the …
index for the development of obesity-related conditions. However, little is known about the …