New perspectives on evolutionary medicine: the relevance of microevolution for human health and disease

FJ Rühli, M Henneberg - BMC medicine, 2013 - Springer
Evolutionary medicine (EM) is a growing field focusing on the evolutionary basis of human
diseases and their changes through time. To date, the majority of EM studies have used …

Type 1 diabetes prevalence increasing globally and regionally: the role of natural selection and life expectancy at birth

WP You, M Henneberg - BMJ open diabetes research and care, 2016 - drc.bmj.com
Objective: Prevalence of type 1 diabetes (T1D) disease is increasing worldwide. We aim to
test correlation of T1D prevalence to the reduced natural selection measured by Biological …

Cancer incidence increasing globally: The role of relaxed natural selection

W You, M Henneberg - Evolutionary applications, 2018 - Wiley Online Library
Cancer incidence increase has multiple aetiologies. Mutant alleles accumulation in
populations may be one of them due to strong heritability of many cancers. The opportunity …

Evolutionary medicine: the ongoing evolution of human physiology and metabolism

F Rühli, K van Schaik, M Henneberg - Physiology, 2016 - journals.physiology.org
The field of evolutionary medicine uses evolutionary principles to understand changes in
human anatomy and physiology that have occurred over time in response to environmental …

Relaxed natural selection contributes to global obesity increase more in males than in females due to more environmental modifications in female body mass

W You, M Henneberg - PloS one, 2018 - journals.plos.org
Objective Relaxed natural selection, measured by Biological State Index (Ibs), results in
unfavourable genes/mutations accumulation in population. Obesity is partly heritable. We …

Worldwide increase of obesity is related to the reduced opportunity for natural selection

A Budnik, M Henneberg - PloS one, 2017 - journals.plos.org
Worldwide rise of obesity may be partly related to the relaxation of natural selection in the
last few generations. Accumulation of mutations affecting metabolism towards excessive fat …

Healthcare services relaxing natural selection may contribute to increase of dementia incidence

W You, R Henneberg, M Henneberg - Scientific Reports, 2022 - nature.com
Ageing and genetic traits can only explain the increasing dementia incidence partially.
Advanced healthcare services allow dementia patients to survive natural selection and pass …

Anatomical variations and evolution: re‐evaluating their importance for surgeons

A Saniotis, M Henneberg - ANZ Journal of Surgery, 2021 - Wiley Online Library
For several decades, anatomists and biological anthropologists have made an intensive
study in anatomical variations in ancestral and living humans. While many anatomical …

Neuro-hormonal regulation is a better indicator of human cognitive abilities than brain anatomy: the need for a new paradigm

A Saniotis, JP Grantham, J Kumaratilake… - Frontiers in …, 2020 - frontiersin.org
Human intelligence has been theorized since the ancient Greeks. Plato and Aristotle
incorporated theories of human intelligence into their metaphysical and cosmological …

Increasing variability of body mass and health correlates in Swiss conscripts, a possible role of relaxed natural selection?

K Staub, M Henneberg, FM Galassi… - … medicine, and public …, 2018 - academic.oup.com
Background and objectives The body mass index (BMI) is an established anthropometric
index for the development of obesity-related conditions. However, little is known about the …