Financial Toxicity of Medical Management of Heart Failure: JACC Review Topic of the Week

S Sukumar, JH Wasfy, JL Januzzi, J Peppercorn… - Journal of the American …, 2023 - jacc.org
Optimal medical management of heart failure (HF) improves quality of life, decreases
mortality, and decreases hospitalizations. Cost may contribute to suboptimal adherence to …

Heart disease prediction using machine learning, deep Learning and optimization techniques-A semantic review

GS Bhavekar, A Das Goswami, CP Vasantrao… - Multimedia Tools and …, 2024 - Springer
Cardiovascular disease holds the position of being the foremost cause of death worldwide.
Heart Disease Prediction (HDP) is a difficult task as it needs advanced knowledge with …

Development of a long‐acting relaxin analogue, LY3540378, for treatment of chronic heart failure

P Verdino, SL Lee, FN Cooper… - British Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Chronic heart failure, a progressive disease with limited
treatment options currently available, especially in heart failure with preserved ejection …

Cardiac troponin activator CK-963 increases cardiac contractility in rats

SE Collibee, A Romero, AR Muci… - Journal of Medicinal …, 2024 - ACS Publications
Novel cardiac troponin activators were identified using a high throughput cardiac myofibril
ATPase assay and confirmed using a series of biochemical and biophysical assays. HTS hit …

Pulmonary artery pressure monitoring in chronic heart failure: effects across clinically relevant subgroups in the MONITOR-HF trial

PRD Clephas, VW Zwartkruis, J Malgie… - European heart …, 2024 - academic.oup.com
Abstract Background and Aims In patients with chronic heart failure (HF), the MONITOR-HF
trial demonstrated the efficacy of pulmonary artery (PA)-guided HF therapy over standard of …

Natriuretic peptide testing and heart failure diagnosis in primary care: diagnostic accuracy study

CJ Taylor, JM Ordóñez-Mena, SL Lay-Flurrie… - British Journal of …, 2023 - bjgp.org
Background Natriuretic peptide (NP) testing is recommended for patients presenting to
primary care with symptoms of chronic heart failure (HF) to prioritise referral for diagnosis …

Heart failure management guidelines: New recommendations and implementation

P Heidenreich - Journal of Cardiology, 2024 - Elsevier
The prevalence of heart failure has increased in many developed countries including Japan
and the USA, due in large part to the aging of their populations. The lifetime risk of heart …

Mechanisms and strategies to promote cardiac xenotransplantation

DJ Garry, JI Weiner, SM Greising, MG Garry… - Journal of Molecular and …, 2022 - Elsevier
End stage heart failure is a terminal disease, and the only curative therapy is orthotopic
heart transplantation. Due to limited organ availability, alternative strategies have received …

Defining the Phenotypes for Heart Failure With Preserved Ejection Fraction

D Rucker, J Joseph - Current heart failure reports, 2022 - Springer
Abstract Purpose of Review Heart failure with preserved ejection fraction (HFpEF) imposes a
significant burden on society and healthcare. The lack in efficacious therapies is likely due to …

The economics of heart failure care

C Wei, PA Heidenreich, AT Sandhu - Progress in Cardiovascular Diseases, 2024 - Elsevier
Heart failure (HF) poses a significant economic burden in the US, with costs projected to
reach $70 billion by 2030. Cost-effectiveness analyses play a pivotal role in assessing the …