In the vast majority of cardiovascular diseases (CVDs), there are well-described differences
between women and men in epidemiology, pathophysiology, clinical manifestations, effects …

Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality.
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …

Background The impact of aortic valve replacement (AVR) on progression/regression of
extravalvular cardiac damage and its association with subsequent prognosis is unknown …

Untreated, severe, symptomatic aortic stenosis is associated with a dismal prognosis. The
only treatment shown to improve survival is aortic valve replacement; however, before …

Background: A differential impact of sex has been observed in transcatheter aortic valve
replacement (TAVR) outcomes from small observational studies and subgroup analyses of …

Background: Left ventricular (LV) hypertrophy, a key process in human cardiac disease,
results from cellular (hypertrophy) and extracellular matrix expansion (interstitial fibrosis) …

Background Greater early left ventricular mass index (LVMi) regression is associated with
fewer hospitalizations 1 year after transcatheter aortic valve replacement (TAVR). The …

Objectives: The aim of this study was to determine the incidence, causes, and predictors of
unplanned hospital readmissions after transcatheter aortic valve replacement (TAVR) …

Objectives: The aim of this study was to evaluate the long-term performance of transcatheter
aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) through …

Importance Data are lacking on the effect of a renin-angiotensin system (RAS) inhibitor
prescribed after transcatheter aortic valve replacement (TAVR). Treatment with a RAS …