Low-Abundance Protein Enrichment for Medical Applications: The Involvement of Combinatorial Peptide Library Technique

E Boschetti, PG Righetti - International Journal of Molecular Sciences, 2023 - mdpi.com
The discovery of low-and very low-abundance proteins in medical applications is
considered a key success factor in various important domains. To reach this category of …

Endometrial cancer diagnostic and prognostic algorithms based on proteomics, metabolomics, and clinical data: a systematic review

A Romano, TL Rižner, HMJ Werner, A Semczuk… - Frontiers in …, 2023 - frontiersin.org
Endometrial cancer is the most common gynaecological malignancy in developed countries.
Over 382,000 new cases were diagnosed worldwide in 2018, and its incidence and mortality …

A label-free proteomic approach for the identification of biomarkers in the exosome of endometrial cancer serum

E Sommella, V Capaci, M Aloisio, E Salviati… - Cancers, 2022 - mdpi.com
Simple Summary Endometrial cancers (ECs) are mostly adenocarcinomas arising from the
inner part of the uterus. The identification of serum biomarkers may be useful for an early …

Phospho-DIGE Identified Phosphoproteins Involved in Pathways Related to Tumour Growth in Endometrial Cancer

V Capaci, G Arrigoni, L Monasta, M Aloisio… - International Journal of …, 2023 - mdpi.com
Endometrial cancer (EC) is the most common gynecologic malignancy of the endometrium.
This study focuses on EC and normal endometrium phosphoproteome to identify …

A Targeted proteomics approach for screening serum biomarkers observed in the early stage of type I endometrial cancer

B Ura, V Capaci, M Aloisio, G Di Lorenzo, F Romano… - Biomedicines, 2022 - mdpi.com
Endometrial cancer (EC) is the most common gynecologic malignancy, and it arises in the
inner part of the uterus. Identification of serum biomarkers is essential for diagnosing the …

[HTML][HTML] Proteomic Profile of Endometrial Cancer: A Scoping Review

B Serambeque, C Mestre, K Hundarova, CM Marto… - Biology, 2024 - mdpi.com
Simple Summary Proteomics can be very useful in identifying proteins, which helps find
potential markers for diseases. Managing endometrial cancer can be difficult and finding …

The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer

V Capaci, F Kharrat, A Conti, E Salviati… - International Journal of …, 2024 - mdpi.com
Among gynecological cancers, endometrial cancer is the most common in developed
countries. Extracellular vesicles (EVs) are cell-derived membrane-surrounded vesicles that …

[HTML][HTML] Navigating the Proteomic Landscape of Menopause: A Review

BE Katamesh, P Futela, A Vincent, B Thilagar… - Medicina, 2024 - mdpi.com
Background and Objectives: Proteomics encompasses the exploration of protein
composition, regulation, function, and pathways. Its influence spans diverse clinical fields …

New Strategies for Endometrial Cancer Detection and Management

L Paleari - International Journal of Molecular Sciences, 2023 - mdpi.com
With 400,000 new cases and over 80,000 deaths a year worldwide, endometrial cancer (EC)
holds a rather unfortunate record, namely, that of the tumour with the highest increase in …

DIGE Analysis of Clinical Specimens

C Gelfi, D Capitanio - Difference Gel Electrophoresis: Methods and …, 2022 - Springer
Two-dimensional difference gel electrophoresis (2D-DIGE) is an elegant gel electrophoretic
analytical tool for comparative protein assessment. It is based on two-dimensional gel …