Mesenchymal stem cell-derived secretome: a potential therapeutic option for autoimmune and immune-mediated inflammatory diseases

G Műzes, F Sipos - Cells, 2022 - mdpi.com
Immune-mediated inflammatory diseases (IMIDs) encompass several entities such as
“classic” autoimmune disorders or immune-mediated diseases with autoinflammatory …

Mesenchymal stromal cells as a driver of inflammaging

S Lyamina, D Baranovskii, E Kozhevnikova… - International Journal of …, 2023 - mdpi.com
Life expectancy and age-related diseases burden increased significantly over the past few
decades. Age-related conditions are commonly discussed in a very limited paradigm of …

Skin boosters: Definitions and varied classifications

KH Yi, W Winayanuwattikun, SY Kim… - Skin Research and …, 2024 - Wiley Online Library
Background The concept of “skin boosters” has evolved, marking a shift from traditional uses
of hyaluronic acid (HA) fillers primarily for augmenting skin volume to a more diverse …

Prospective use of amniotic mesenchymal stem cell metabolite products for tissue regeneration

A Miatmoko, BS Hariawan, DM Cahyani… - Journal of Biological …, 2023 - Springer
Chronic disease can cause tissue and organ damage constituting the largest obstacle to
therapy which, in turn, reduces patients' quality-adjusted life-year. Degenerative diseases …

Effectiveness of secretome from human umbilical cord mesenchymal stem cells in gel (10% SM-hUCMSC Gel) for chronic wounds (Diabetic and Trophic Ulcer)–Phase …

ST Tan, PB Aisyah, Y Firmansyah… - Journal of …, 2023 - Taylor & Francis
Background Chronic wounds carry financial burdens and increase morbidity and mortality,
especially in diabetic ulcers and Hansen's Morbus. More than 50% of chronic ulcers are …

Mesenchymal stem cells-derived secretome and extracellular vesicles: perspective and challenges in cancer therapy and clinical applications

J Gemayel, D Chaker, G El Hachem, M Mhanna… - Clinical and …, 2023 - Springer
Stem cell-based therapies have been foreshowed as a promising therapeutic approach for
the treatment of several diseases. However, in the cancer context, results obtained from …

Image-based crosstalk analysis of cell–cell interactions during sprouting angiogenesis using blood-vessel-on-a-chip

T Sano, T Nakajima, KA Senda, S Nakano… - Stem Cell Research & …, 2022 - Springer
Background Sprouting angiogenesis is an important mechanism for morphogenetic
phenomena, including organ development, wound healing, and tissue regeneration. In …

[HTML][HTML] Isolation of lysozyme producing Bacillus subtilis Strains, identification of the new strain Bacillus subtilis BSN314 with the highest enzyme production capacity …

M Naveed, H Tianying, F Wang, X Yin… - Current Research in …, 2022 - Elsevier
Lysozyme is a naturally occurring enzyme that is ubiquitous and plays an important role in
innate immunity through its potent bacteriolytic activity. The main objective of this study was …

Influence of periodontal ligament stem cell-derived conditioned medium on osteoblasts

S Novello, S Tricot-Doleux, A Novella, P Pellen-Mussi… - Pharmaceutics, 2022 - mdpi.com
Mesenchymal stem cells (MSC) are involved in the regeneration of various missing or
compromised periodontal tissues, including bone. MSC-derived conditioned medium (CM) …

Progress in the development of stem cell-derived cell-free therapies for skin aging

Y Chou, NM Alfarafisa, M Ikezawa… - Clinical, Cosmetic and …, 2023 - Taylor & Francis
Introduction The skin is a vital organ as the body's largest barrier, but its function declines
with aging. Therefore, research into effective regeneration treatments must continue to …