Myzozoans encompass apicomplexans and dinoflagellates that manifest diverse lifestyles in
highly varied environments. They show enormous propensity to employ different metabolic …

In the apicomplexans, endocytosed cargos (eg, hemoglobin) are trafficked to a specialized
organelle for digestion. This follows a unique endocytotic process at the …

Iron is essential to cells as a cofactor in enzymes of respiration and replication, however
without correct storage, iron leads to the formation of dangerous oxygen radicals. In yeast …

Apicomplexan parasites are a group of protists that cause disease in humans and include
pathogens like Plasmodium spp., the causative agent of malaria, and Toxoplasma gondii …

Toxoplasma gondii possesses a highly polarized secretory pathway that contains both
broadly conserved eukaryotic organelles and unique apicomplexan organelles, which play …

As an obligate intracellular parasite, Toxoplasma gondii must import essential nutrients from
the host cell into the parasitophorous vacuole. We previously reported that the parasite …

Toxoplasma gondii is a protozoan parasite that infects a broad spectrum of hosts and can
colonize many organs and cell types. The ability to reside within a wide range of different …

Protozoan parasites cause life‐threatening infections in both humans and animals, including
agriculturally significant livestock. Available treatments are typically narrow spectrum and …

The protozoan Toxoplasma gondii (T. gondii) is a zoonotic disease agent causing systemic
infection in warm-blooded intermediate hosts including humans. During the acute infection …

Endocytosis is a quintessential feature of eukaryotes, and the emergence of endocytosis
played a major role in the origin and evolution of eukaryotes. During the early evolution of …