The review is mainly focused on application of thin layer chromatography (TLC) as simple,
rapid and inexpensive method for lipophilicity assessment. Among separation techniques …

In this paper, thiosemicarbazide derivatives were synthesized as potential anticancer
agents. X-ray investigations for 1-(2, 4-dichlorophenoxy) acetyl-4-(2-fluorophenyl) …

The physicochemical properties of small molecules that can be determined by retention
measurements in reversed-phase liquid chromatography include solvent-based properties …

In this chapter we strive to provide a comprehensive but reasonably compact overview of the
various possibilities for the computational representation of molecules. This includes a …

Needs for fast, yet reliable means of assessing the lipophilicities of diverse compounds
resulted in the development of various in silico and chromatographic approaches that are …

Lipophilicity in addition to the solubility, acid-base character and stability is one of the most
important physicochemical parameters of a compound required to assess the ADMET …

Lipophilicity is one of the most frequently used physicochemical properties that affects
compound solubility, determines its passive transport through biological membranes …

Lipophilicity is a vital physicochemical parameter of a molecule, which affects several
biological processes such as absorption, tissue distribution, and pharmacokinetic properties …

The objective of this study was to model the retention of nucleosides and pterins in
hydrophilic interaction liquid chromatography (HILIC) via QSRR-based approach. Two home …

Naturally occurring molecules are excellent sources of lead compounds. A series of
oleanolic acid (OA) derivatives previously synthesized in our laboratory, which show …