Obesity is a chronic disease with a continuously rising prevalence that currently affects more
than half a billion people worldwide. Energy balance and appetite are highly regulated via …

In the midst of an obesity epidemic, the promotion of brown adipose tissue (BAT) function
and the browning of white adipose tissue (WAT) have emerged as promising therapeutic …

New appetite‐regulating antiobesity treatments such as semaglutide and agents under
investigation such as tirzepatide show promise in achieving weight loss of 15% or more …

Whether bone marrow modulates systemic metabolism remains unknown. Our recent study
suggested that myeloid-derived growth factor (MYDGF) improves insulin resistance. Here …

Obesity is a growing civilization problem, associated with a number of negative health
consequences affecting almost all tissues and organs. Currently, obesity treatment includes …

Abstract Uncoupling protein 1 (UCP1) has been discovered as a possible target for obesity
treatment because of its widespread distribution in the inner mitochondrial membrane of …

Brown and brite adipocytes contribute to energy expenditure through nonshivering
thermogenesis. Though these cell types are thought to arise primarily from the de novo …

Human brown adipose tissue (BAT) was re-discovered in 2009 by several independent
groups, who showed that it is present and active in adults, as judged from the profound …

Brown adipose tissue (BAT) is proposed to maintain thermal homeostasis through
dissipation of chemical energy as heat by the uncoupling proteins (UCPs) present in their …

The disease criteria used by the World Health Organization (WHO) were applied to human
biological aging in order to assess whether aging can be classified as a disease. These …