The prevalence of obesity has tripled over the past four decades, imposing an enormous
burden on people's health. Polygenic (or common) obesity and rare, severe, early-onset …

Brain-derived neurotrophic factor (BDNF) is a neuropeptide that plays numerous important
roles in synaptic development and plasticity. While its importance in fundamental physiology …

Using behavioral, pharmacological, and molecular methods, lots of studies reveal that
depression is closely related to the abnormal neural plasticity processes occurring in the …

Exercise is known to have numerous neuroprotective and cognitive benefits, especially
pertaining to memory and learning related processes. One potential link connecting them is …

Brain-derived neurotrophic factor (BDNF) belongs to a family of small secreted proteins that
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …

Among all neurotrophins, brain-derived neurotrophic factor (BDNF) stands out for its high
level of expression in the brain and its potent effects on synapses. It is now widely accepted …

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of secreted
proteins. Signaling cascades induced by BDNF and its receptor, the receptor tyrosine kinase …

Brain-derived neurotrophic factor (BDNF)—a member of a small family of secreted proteins
that includes nerve growth factor, neurotrophin 3 and neurotrophin 4—has emerged as a …

Therapeutic deficiencies with monoaminergic antidepressants invites the need to identify
and develop novel rapid-acting antidepressants. Hitherto, ketamine and esketamine are …

Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …