Molecular mechanisms responsible for therapeutic potential of mesenchymal stem cell-derived secretome
CR Harrell, C Fellabaum, N Jovicic, V Djonov… - Cells, 2019 - mdpi.com
Mesenchymal stem cell (MSC)-sourced secretome, defined as the set of MSC-derived
bioactive factors (soluble proteins, nucleic acids, lipids and extracellular vesicles), showed …
bioactive factors (soluble proteins, nucleic acids, lipids and extracellular vesicles), showed …
Concise review: multifaceted characterization of human mesenchymal stem cells for use in regenerative medicine
RM Samsonraj, M Raghunath… - Stem cells …, 2017 - academic.oup.com
Mesenchymal stem cells (MSC) hold great potential for regenerative medicine because of
their ability for self-renewal and differentiation into tissue-specific cells such as osteoblasts …
their ability for self-renewal and differentiation into tissue-specific cells such as osteoblasts …
Clinical trials with mesenchymal stem cells: an update
T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …
regenerative properties and ability to differentiate into diverse cell lineages, have generated …
The immunomodulatory functions of mesenchymal stromal/stem cells mediated via paracrine activity
Y Zhou, Y Yamamoto, Z Xiao, T Ochiya - Journal of clinical medicine, 2019 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) exist in almost all tissues, possessing the potential
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …
Role of mesenchymal stem cells in bone regenerative medicine: what is the evidence?
Healing and regeneration of bone injuries, particularly those that are associated with large
bone defects, are a complicated process. There is growing interest in the application of …
bone defects, are a complicated process. There is growing interest in the application of …
Acute-on-chronic liver failure: terminology, mechanisms and management
SK Sarin, A Choudhury - Nature Reviews Gastroenterology & …, 2016 - nature.com
Acute-on-chronic liver failure (ACLF) is a distinct clinical entity and differs from acute liver
failure and decompensated cirrhosis in timing, presence of acute precipitant, course of …
failure and decompensated cirrhosis in timing, presence of acute precipitant, course of …
hucMSC exosome-derived GPX1 is required for the recovery of hepatic oxidant injury
Y Yan, W Jiang, Y Tan, S Zou, H Zhang, F Mao… - Molecular Therapy, 2017 - cell.com
Exosomes are small biological membrane vesicles secreted by various cells, including
mesenchymal stem cells (MSCs). We previously reported that MSC-derived exosomes (MSC …
mesenchymal stem cells (MSCs). We previously reported that MSC-derived exosomes (MSC …
Pathogenesis, early diagnosis, and therapeutic management of alcoholic liver disease
LZ Kong, N Chandimali, YH Han, DH Lee… - International journal of …, 2019 - mdpi.com
Alcoholic liver disease (ALD) refers to the damages to the liver and its functions due to
alcohol overconsumption. It consists of fatty liver/steatosis, alcoholic hepatitis …
alcohol overconsumption. It consists of fatty liver/steatosis, alcoholic hepatitis …
BMSCs-derived miR-223-containing exosomes contribute to liver protection in experimental autoimmune hepatitis
L Chen, F Lu, D Chen, J Wu, L Xu, M Zheng, H Li… - Molecular …, 2018 - Elsevier
Autoimmune hepatitis is a chronic inflammatory disease in the liver with potential to the
development of liver fibrosis. Recent evidences suggest that bone marrow derived …
development of liver fibrosis. Recent evidences suggest that bone marrow derived …
Cell and tissue engineering for liver disease
Despite the tremendous hurdles presented by the complexity of the liver's structure and
function, advances in liver physiology, stem cell biology and reprogramming, and the …
function, advances in liver physiology, stem cell biology and reprogramming, and the …