Heart valves (HVs) are fluidic control components of the heart that ensure unidirectional
blood flow during the cardiac cycle. However, this description does not adequately describe …

Surgical replacement of diseased heart valves by mechanical and tissue valve substitutes is
now commonplace and enhances survival and quality of life for many patients. However …

In this paper, we develop a geometrically flexible technique for computational fluid–structure
interaction (FSI). The motivating application is the simulation of tri-leaflet bioprosthetic heart …

We present formulations for compressible and incompressible hyperelastic thin shells which
can use general 3D constitutive models. The necessary plane stress condition is enforced …

We propose a framework that combines variational immersed-boundary and arbitrary
Lagrangian–Eulerian methods for fluid–structure interaction (FSI) simulation of a …

This paper builds on a recently developed immersogeometric fluid–structure interaction
(FSI) methodology for bioprosthetic heart valve (BHV) modeling and simulation. It enhances …

Numerous studies have suggested that medical image derived computational mechanics
models could be developed to reduce mortality and morbidity due to cardiovascular …

We investigate the use of Isogeometric Analysis for the model construction and simulation of
aortic valve closure. We obtain converged results and compare with benchmark finite …

Transcatheter aortic valve (TAV) intervention is now the standard-of-care treatment for
inoperable patients and a viable alternative treatment option for high-risk patients with …

Computer modeling and simulation is a powerful tool for assessing the performance of
medical devices such as bioprosthetic heart valves (BHVs) that promises to accelerate …