Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches
Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …
[HTML][HTML] The systemic nature of CKD
The accurate definition and staging of chronic kidney disease (CKD) is one of the major
achievements of modern nephrology. Intensive research is now being undertaken to unravel …
achievements of modern nephrology. Intensive research is now being undertaken to unravel …
Inflammation and premature ageing in chronic kidney disease
T Ebert, SC Pawelzik, A Witasp, S Arefin, S Hobson… - Toxins, 2020 - mdpi.com
Persistent low-grade inflammation and premature ageing are hallmarks of the uremic
phenotype and contribute to impaired health status, reduced quality of life, and premature …
phenotype and contribute to impaired health status, reduced quality of life, and premature …
Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia
J Voelkl, F Lang, KU Eckardt, K Amann… - Cellular and Molecular …, 2019 - Springer
Medial vascular calcification has emerged as a putative key factor contributing to the
excessive cardiovascular mortality of patients with chronic kidney disease (CKD) …
excessive cardiovascular mortality of patients with chronic kidney disease (CKD) …
Alkaline phosphatase: a novel treatment target for cardiovascular disease in CKD
M Haarhaus, V Brandenburg… - Nature Reviews …, 2017 - nature.com
Cardiovascular disease is the main cause of early death in the settings of chronic kidney
disease (CKD), type 2 diabetes mellitus (T2DM), and ageing. Cardiovascular events can be …
disease (CKD), type 2 diabetes mellitus (T2DM), and ageing. Cardiovascular events can be …
Review of potential health risks associated with nanoscopic calcium phosphate
M Epple - Acta biomaterialia, 2018 - Elsevier
Calcium phosphate is applied in many products in biomedicine, but also in toothpastes and
cosmetics. In some cases, it is present in nanoparticulate form, either on purpose or after …
cosmetics. In some cases, it is present in nanoparticulate form, either on purpose or after …
A randomized trial of magnesium oxide and oral carbon adsorbent for coronary artery calcification in predialysis CKD
Background Developing strategies for managing coronary artery calcification (CAC) in
patients with CKD is an important clinical challenge. Experimental studies have …
patients with CKD is an important clinical challenge. Experimental studies have …
Chronic kidney disease circulating calciprotein particles and extracellular vesicles promote vascular calcification: a role for GRP (Gla-Rich Protein)
CSB Viegas, L Santos, AL Macedo… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Inhibition of mineral crystal formation is a crucial step in ectopic calcification.
Serum calciprotein particles (CPPs) have been linked to chronic kidney disease (CKD) …
Serum calciprotein particles (CPPs) have been linked to chronic kidney disease (CKD) …
The importance of being amorphous: calcium and magnesium phosphates in the human body
This article focuses on the relevance of amorphous calcium (and magnesium) phosphates in
living organisms. Although crystalline calcium phosphate (CaP)-based materials are known …
living organisms. Although crystalline calcium phosphate (CaP)-based materials are known …
The effect of increasing dialysate magnesium on serum calcification propensity in subjects with end stage kidney disease: a randomized, controlled clinical trial
I Bressendorff, D Hansen, M Schou… - Clinical Journal of the …, 2018 - journals.lww.com
Results Fifty-nine subjects were enrolled in the trial, and of these, 57 completed the
intervention and were analyzed for the primary outcome. In the standard dialysate …
intervention and were analyzed for the primary outcome. In the standard dialysate …