BIRC3 and BIRC5: multi‐faceted inhibitors in cancer
R Frazzi - Cell & bioscience, 2021 - Springer
Background The evasion from apoptosis is a common strategy adopted by most tumors, and
inhibitors of apoptosis proteins (IAPs) are among the most studied molecular and …
inhibitors of apoptosis proteins (IAPs) are among the most studied molecular and …
Role of microRNAs in lung development and pulmonary diseases
MicroRNAs (miRNAs) are a class of small noncoding RNA which exert post-transcriptional
gene regulation activity by targeting messenger RNAs. miRNAs have been found to be …
gene regulation activity by targeting messenger RNAs. miRNAs have been found to be …
Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells
PC Hollenhorst, MW Ferris, MA Hull… - Genes & …, 2011 - genesdev.cshlp.org
The aberrant expression of an oncogenic ETS transcription factor is implicated in the
progression of the majority of prostate cancers, 40% of melanomas, and most cases of …
progression of the majority of prostate cancers, 40% of melanomas, and most cases of …
MicroRNA‐204‐5p: A pivotal tumor suppressor
MicroRNAs (miRNAs) are a class of non‐coding single‐stranded RNA molecules with a
length of approximately 18‐25 nt nucleotides that regulate gene expression post …
length of approximately 18‐25 nt nucleotides that regulate gene expression post …
The dual regulatory role of miR-204 in cancer
T Li, H Pan, R Li - Tumor Biology, 2016 - Springer
MicroRNAs (miRNAs) are a group of endogenous, small (about 22 nucleotides) non-coding
RNAs which negatively regulate gene expressions. As one of them, miR-204 originates from …
RNAs which negatively regulate gene expressions. As one of them, miR-204 originates from …
MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1
L Shi, B Zhang, X Sun, S Lu, Z Liu, Y Liu, H Li… - British journal of …, 2014 - nature.com
Background: Lung cancer is a leading cause of cancer-related mortality worldwide and non-
small-cell lung carcinoma (NSCLC) is responsible for almost 80% of lung cancer-related …
small-cell lung carcinoma (NSCLC) is responsible for almost 80% of lung cancer-related …
Understanding the role of ETS-mediated gene regulation in complex biological processes
VJ Findlay, AC LaRue, DP Turner, PM Watson… - Advances in cancer …, 2013 - Elsevier
Ets factors are members of one of the largest families of evolutionarily conserved
transcription factors, regulating critical functions in normal cell homeostasis, which when …
transcription factors, regulating critical functions in normal cell homeostasis, which when …
SPDEF inhibits prostate carcinogenesis by disrupting a positive feedback loop in regulation of the Foxm1 oncogene
XH Cheng, M Black, V Ustiyan, T Le, L Fulford… - PLoS …, 2014 - journals.plos.org
SAM-pointed domain-containing ETS transcription factor (SPDEF) is expressed in normal
prostate epithelium. While its expression changes during prostate carcinogenesis (PCa), the …
prostate epithelium. While its expression changes during prostate carcinogenesis (PCa), the …
[HTML][HTML] A dual yet opposite growth-regulating function of miR-204 and its target XRN1 in prostate adenocarcinoma cells and neuroendocrine-like prostate cancer …
M Ding, B Lin, T Li, Y Liu, Y Li, X Zhou, M Miao, J Gu… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Androgen deprivation therapy in prostate cancer (PCa) causes neuroendocrine
differentiation (NED) of prostatic adenocarcinomas (PAC) cells, leading to recurrence of …
differentiation (NED) of prostatic adenocarcinomas (PAC) cells, leading to recurrence of …
ETS transcription factors in hematopoietic stem cell development
A Ciau-Uitz, L Wang, R Patient, F Liu - Blood Cells, Molecules, and …, 2013 - Elsevier
Hematopoietic stem cells (HSCs) are essential for the maintenance of the hematopoietic
system. However, these cells cannot be maintained or created in vitro, and very little is …
system. However, these cells cannot be maintained or created in vitro, and very little is …