The potential of metabolomics in biomedical applications

V Gonzalez-Covarrubias, E Martínez-Martínez… - Metabolites, 2022 - mdpi.com
The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …

Food addiction: a valid concept?

PC Fletcher, PJ Kenny - Neuropsychopharmacology, 2018 - nature.com
Can food be addictive? What does it mean to be a food addict? Do common underlying
neurobiological mechanisms contribute to drug and food addiction? These vexing questions …

[HTML][HTML] The cafeteria diet: A standardized protocol and its effects on behavior

JF Lalanza, EMS Snoeren - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Obesity is a major health risk, with junk food consumption playing a central role in weight
gain, because of its high palatability and high-energy nutrients. The Cafeteria (CAF) diet …

Neural vulnerability factors for obesity

E Stice, K Burger - Clinical psychology review, 2019 - Elsevier
Multiple theories identify neural vulnerability factors that may increase risk for overeating
and weight gain. Early cross-sectional neuroimaging studies were unable to determine …

Endocannabinoid modulation of homeostatic and non-homeostatic feeding circuits

BK Lau, D Cota, L Cristino, SL Borgland - Neuropharmacology, 2017 - Elsevier
The endocannabinoid system has emerged as a key player in the control of eating.
Endocannabinoids, including 2-arachidonoylglycerol (2-AG) and anandamide (AEA) …

The orbitofrontal cortex, food intake and obesity

LT Seabrook, SL Borgland - Journal of Psychiatry and Neuroscience, 2020 - jpn.ca
Obesity is a major health challenge facing many people throughout the world. Increased
consumption of palatable, high-caloric foods is one of the major drivers of obesity. Both …

Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice

N Fadahunsi, J Lund, AW Breum, CV Mathiesen… - Translational …, 2022 - nature.com
Psilocybin and other serotonergic psychedelics have re-emerged as therapeutics for
neuropsychiatric disorders, including addiction. Psilocybin induces long-lasting effects on …

Organization of afferents to the orbitofrontal cortex in the rat

MJM Murphy, AY Deutch - Journal of Comparative Neurology, 2018 - Wiley Online Library
The prefrontal cortex (PFC) is usually defined as the frontal cortical area receiving a
mediodorsal thalamic (MD) innervation. Certain areas in the medial wall of the rat frontal …

Obesity-related neuroinflammation: magnetic resonance and microscopy imaging of the brain

A Woo, A Botta, SSW Shi, T Paus… - International Journal of …, 2022 - mdpi.com
Obesity is a major risk factor of Alzheimer's disease and related dementias. The principal
feature of dementia is a loss of neurons and brain atrophy. The mechanistic links between …

Neural mechanisms underlying the role of fructose in overfeeding

MA Payant, MJ Chee - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Fructose consumption has been linked with metabolic syndrome and obesity. Fructose-
based sweeteners like high fructose corn syrup taste sweeter, improve food palatability, and …