Cell migration is an adaptive process that depends on and responds to physical and
molecular triggers. Moving cells sense and respond to tissue mechanics and induce …

Leukocytes can completely reorganize their cytoskeletal architecture within minutes. This
structural plasticity, which facilitates their migration and communicative function, also …

The mesenchymal-amoeboid transition (MAT) was proposed as a mechanism for cancer
cells to adapt their migration mode to their environment. While the molecular pathways …

Tendon is an intricately organized connective tissue that efficiently transfers muscle force to
the bony skeleton. Its structure, function, and physiology reflect the extreme, repetitive …

During cell migration, the forces generated in the actin cytoskeleton are transmitted across
transmembrane receptors to the extracellular matrix or other cells through a series of …

Eukaryotic cells migrate by coupling the intracellular force of the actin cytoskeleton to the
environment. While force coupling is usually mediated by transmembrane adhesion …

The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

Cell movement has essential functions in development, immunity, and cancer. Various cell
migration patterns have been reported, but no general rule has emerged so far. Here, we …

Cell migration has two opposite faces: although necessary for physiological processes such
as immune responses, it can also have detrimental effects by enabling metastatic cells to …

Cell migration is central to a multitude of physiological processes, including embryonic
development, immune surveillance, and wound healing, and deregulated migration is key to …