Lead (Pb) pollution has been considered as a major threat for human health due to
induction of inflammatory cascades in various tissues. The aim of present review is to …

The term epigenetics was coined in the context of developmental studies, but the meaning of
the term has evolved over time. Epigenetic modulators of gene expression are now known to …

The battery industry is the largest consumer of lead, using an estimated 80% of the global
lead production. The industry is also rapidly expanding in emerging market countries. A …

There are many discrepancies among the results of studies on the genotoxicity of lead. The
aim of the study was to explore lead-induced DNA damage, including oxidative damage, in …

Abstract δ-ALA-D is a metalloenzyme that has 3 vicinal thiol/thiolate groups that coordinate
with Zn (ii). The proximity between the sulfhydryl groups renders δ-ALA-D extremely …

Millions of humans are exposed occupationally and environmentally to lead, mercury and
cadmium compounds. Mercury compounds are less abundant but some of them belong to …

Occupational exposure to heavy metals like lead and cadmium causes a wide range of
biological effects and may elevate the risk of genetic damage. Heavy metal toxicity is now …

Studies suggest that chronic lead (Pb) exposure may induce deoxyribonucleic acid (DNA)
damage. However, there is no synthesised evidence in this regard. We systematically …

Lead is still widely used in many industrial processes and is very persistent in the
environment. Although toxic effects caused by occupational exposure to lead have been …

Environmental toxicants such as toxic metals can alter epigenetic regulatory features such
as DNA methylation, histone modification, and non-coding RNA expression. Heavy metals …