Abstract mRNA vaccines have emerged as a revolutionary tool to generate rapid and
precise immune responses against infectious diseases and cancers. Compared with …

Dietary fibers are plant-derived carbohydrates and associated components, that are not
digested within the human upper intestinal tract/gut. Traditionally they are classified based …

Microbially derived short-chain fatty acids (SCFAs) in the human gut are tightly coupled to
host metabolism, immune regulation and integrity of the intestinal epithelium. However, the …

Nutrition profoundly shapes immunity and inflammation across the lifespan of mammals,
from pre-and post-natal periods to later life. Emerging insights into diet-microbiota …

“Dietary fiber”(DF) refers to a type of carbohydrate that cannot be digested fully. DF is not an
essential nutrient, but it plays an important part in enhancing digestive capacity and …

Background Food systems worldwide have become industrialized over the past century with
impacts on diets, nutrition and health. The trade-offs between affordability and higher-quality …

Diet is intimately linked to the gastrointestinal (GI) tract and has potent effects on intestinal
immune homeostasis. Inflammatory bowel disease (IBD) is characterized by chronic …

Background The observation that the intestinal microbiota is central in the development of
IBD suggests that dietary fiber, the microbiota's primary source of nourishment, could play a …

Background The continuous proliferation of intestinal stem cells followed by their tightly
regulated differentiation to epithelial cells is essential for the maintenance of the gut …

Dietary fiber is degraded by commensal gut microbes to yield host-beneficial short-chain
fatty acids (SCFAs), but personalized responses to fiber supplementation highlight a role for …