Understanding and controlling interfaces has proven to be key to a very wide range of
applications, from optical and electronic materials 1, 2 to energy storage and production, 3 …

In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …

Joint replacement is a major orthopaedic procedure used to treat joint osteoarthritis. Aseptic
loosening and infection are the two most significant causes of prosthetic implant failure. The …

Immune checkpoint inhibitors (ICIs) can reinvigorate T cells to eradicate tumor cells,
showing great potential in combating various types of tumors. We propose a delivery …

Directed cell migration is a physical process that requires dramatic changes in cell shape
and adhesion to the extracellular matrix. For efficient movement, these processes must be …

Binding of integrins to ligands provides anchorage and signals for the cell, making them
prime candidates for mechanosensing molecules. How force regulates integrin–ligand …

Modern synthetic biomaterials are being designed to integrate bioactive ligands within
hydrogel scaffolds for cells to respond and assimilate within the matrix. These advanced …

Principles of Regenerative Medicine, Third Edition, details the technologies and advances
applied in recent years to strategies for healing and generating tissue. Contributions from a …

Mesenchymal stem cells (MSC) represent a promising and clinically relevant cell source for
tissue engineering applications. As such, guiding MSCs toward specific lineages and …

Generally, medical implants, regardless of their construction materials, will become coated
in a layer of nonspecific proteins mere seconds after implantation. This adsorbed layer …