[HTML][HTML] Defining the role of the MHC in autoimmunity: a review and pooled analysis

MMA Fernando, CR Stevens, EC Walsh… - PLoS …, 2008 - journals.plos.org
The major histocompatibility complex (MHC) is one of the most extensively studied regions
in the human genome because of the association of variants at this locus with autoimmune …

Is there a future for TNF promoter polymorphisms?

JP Bayley, THM Ottenhoff, CL Verweij - Genes & Immunity, 2004 - nature.com
The in vitro study of TNF promoter polymorphism (SNP) function was stimulated by the
numerous case–control (association) studies of the polymorphisms in relation to human …

A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis

MR Lincoln, A Montpetit, MZ Cader, J Saarela… - Nature …, 2005 - nature.com
Genetic susceptibility to multiple sclerosis is associated with genes of the major
histocompatibility complex (MHC), particularly HLA-DRB1 and HLA-DQB1 (ref.). Both locus …

Cytokines in multiple sclerosis: from bench to bedside

J Imitola, T Chitnis, SJ Khoury - Pharmacology & therapeutics, 2005 - Elsevier
Cytokines play an important role in the pathogenesis of inflammatory diseases including
multiple sclerosis (MS). Experimental models have played a critical role in unraveling the …

Infection, inflammation and the risk of cerebral palsy

KB Nelson, RE Willoughby - Current opinion in neurology, 2000 - journals.lww.com
The balance of current evidence indicates that intrauterine exposure to infection and
inflammation contributes to the risk of cerebral palsy. The mechanisms involved are not well …

[HTML][HTML] Genetics of inflammatory bowel disease: the role of the HLA complex

T Ahmad, SE Marshall, D Jewell - World journal of …, 2006 - ncbi.nlm.nih.gov
The human leucocyte antigen (HLA) complex on chromosome 6p21. 3 is the most
extensively studied genetic region in Inflammatory bowel disease (IBD). Consistent …

ISSLS PRIZE IN CLINICAL SCIENCE 2018: longitudinal analysis of inflammatory, psychological, and sleep-related factors following an acute low back pain episode …

DM Klyne, MF Barbe, W van den Hoorn… - European Spine …, 2018 - Springer
Study design Prospective longitudinal study. Objective To determine whether systemic
cytokines and C-reactive protein (CRP) during an acute episode of low back pain (LBP) …

Genes in the HLA class I region may contribute to the HLA class II‐associated genetic susceptibility to multiple sclerosis

HF Harbo, BA Lie, S Sawcer, EG Celius, KZ Dai… - Tissue …, 2004 - Wiley Online Library
In order to analyze whether loci in the human leukocyte antigen (HLA) class I region may
contribute to the HLA class II‐associated genetic susceptibility to multiple sclerosis (MS), we …

(Peri) vascular production and action of pro-inflammatory cytokines in brain pathology

JP Konsman, B Drukarch, AM Van Dam - Clinical science, 2007 - portlandpress.com
In response to tissue injury or infection, the peripheral tissue macrophage induces an
inflammatory response through the release of IL-1β (interleukin-1β) and TNFα (tumour …

Retrobulbar optic neuritis associated with infliximab

R Foroozan, LM Buono, RC Sergott… - Archives of …, 2002 - jamanetwork.com
© 2002 American Medical Association. All rights reserved. foci of abundant xanthoid cells
and areas of focally dense lymphoid infiltrates. These features are strongly suggestive of …