The discovery of Helicobacter pylori overturned the conventional dogma that the stomach
was a sterile organ and that pH values< 4 were capable of sterilizing the stomach. H. pylori …

Since the discovery of LGR5 as a marker of intestinal stem cells, the field has developed
explosively and led to many new avenues of research. The inner workings of the intestinal …

JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 2007, 58, Suppl 1, 13 35 www. jpp.
krakow. pl postprandially in both OB-MS and MOB-MS, it was much lower than in lean …

Helicobacter Pylori is a gram negative rod shaped microaerophilic bacterium that colonizes
the stomach of approximately half the world's population. Infection with c may cause chronic …

Background VISION is a randomised, phase 4, open-label, parallel-group, multicentre study
conducted in 33 centres in Japan. The aim of this study was to assess the long-term safety of …

Gastrin is a pro-proliferative, anti-apoptotic hormone with a central role in acid secretion in
the gastric mucosa and a long-standing association with malignant progression in …

The dramatic success of pharmacological acid suppression in healing peptic ulcers and
managing patients with gastroesophageal reflux disease (GERD) has been reflected in the …

Gastric cancer is the third leading cause of cancer-related mortality worldwide. Despite
progress in understanding its development, challenges with treatment remain. Gastrin, a …

Objectives: Increasing evidence suggested that proton pump inhibitors (PPIs) use might
affect the development of cancers, but previous conclusions remain controversial. Therefore …

In this paper, the estabished and possible roles of CCK1 and CCK2 receptors in
gastrointestinal (GI) and metabolic diseases are reviewed and available results from human …