An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets

J Griger, SA Widholz, M Jesinghaus… - Cancer Cell, 2023 - cell.com
Gastric neuroendocrine carcinomas (G-NEC) are aggressive malignancies with poorly
understood biology and a lack of disease models. Here, we use genome sequencing to …

Genome-wide in vivo screens link regulatory principles and phenotype evolution in T cell leukemia

A Fischer - 2023 - mediatum.ub.tum.de
Cancer evolution is characterized by extensive changes of regulatory landscapes, which are
poorly understood at the functional level. This work describes genome-wide screening …